C12N 5/0645
Macrophages
Official title: {Macrophages, e.g. Kuepfer cells in the liver; Monocytes}
C12N5/0645 (Macrophages) appears on 298 US grants and 697 published applications in this corpus.
Search patents in C12N- Granted patents
- 298
- Published applications
- 697
- Assignees
- 426
- Inventors
- 1,497
- Latest grant
- 6 Oct 2026
Filings by year
| Year | Granted patents | Published applications |
|---|---|---|
| 1992 | 1 | 0 |
| 1993 | 0 | 0 |
| 1994 | 0 | 0 |
| 1995 | 1 | 0 |
| 1996 | 2 | 0 |
| 1997 | 2 | 0 |
| 1998 | 3 | 0 |
| 1999 | 1 | 0 |
| 2000 | 7 | 0 |
| 2001 | 4 | 1 |
| 2002 | 3 | 13 |
| 2003 | 3 | 3 |
| 2004 | 5 | 9 |
| 2005 | 2 | 9 |
| 2006 | 2 | 8 |
| 2007 | 1 | 3 |
| 2008 | 1 | 7 |
| 2009 | 0 | 10 |
| 2010 | 3 | 6 |
| 2011 | 2 | 8 |
| 2012 | 1 | 12 |
| 2013 | 8 | 13 |
| 2014 | 12 | 17 |
| 2015 | 9 | 22 |
| 2016 | 14 | 18 |
| 2017 | 9 | 27 |
| 2018 | 9 | 39 |
| 2019 | 13 | 33 |
| 2020 | 16 | 48 |
| 2021 | 24 | 64 |
| 2022 | 28 | 80 |
| 2023 | 26 | 58 |
| 2024 | 35 | 61 |
| 2025 | 31 | 62 |
| 2026 | 20 | 66 |
By publication year. Applications have been published since 2001. 2026 runs to 8 Oct.
Recent patents
- Engineered cells and uses thereof6 Oct 2026US 12,751,929 B2Ohio State Innovation Foundation
- Genetically engineered phagocytes, and related compositions, vectors, methods and systems22 Sep 2026US 12,741,025 B2The Regents of the University of California
- Targeting the human CCR5 locus as a safe harbor for the expression of therapeutic proteins15 Sep 2026US 12,735,711 B2The Board of Trustees of the Leland Stanford Junior University
- Tumor immunotherapy composition based on antigen-presenting cells activated by attenuated listeria monocytogenes, preparation method therefor and application thereof11 Aug 2026US 12,702,681 B2Shanghai RoyalTech Med CO., Ltd
- Kits, compositions and methods for cell enrichment28 Jul 2026US 12,692,308 B2Stemcell Technologies Canada Inc.
- Application of CCR5hi Innate Immune Memory Cells in Preparation of Immunotherapeutic Drug for Treating Sepsis8 Oct 2026US 2026/0306538 A1Children's Hospital of Soochow University
- Modulation of b-cell translocation gene 1 (btg1) for use in adoptive cell therapy1 Oct 2026US 2026/0294968 A1Baylor College of Medicine
- Patrolling monocyte cellular therapy1 Oct 2026US 2026/0297525 A1New York Blood Center, Inc.
- SIRPalpha Knockout iPSC-derived and CAR-comprising Macrophages with Enhanced Anti-tumor Activity24 Sep 2026US 2026/0284104 A1Wisconsin Alumni Research Foundation
- Patient specific induced pluripotent stem cell derived macrophages for cell based therapy24 Sep 2026US 2026/0284107 A1Board of Regents, The University of Texas System
Most cited
By later US patents
- Method for promoting hematopoietic and mesenchymal cell proliferation and differentiation139US 6,335,195 B12002
- Method for promoting mesenchymal stem and lineage-specific cell proliferation122US 6,248,587 B1University of Southern Cailfornia · 2001
- Dendritic-marker expressing macrophage cultures and methods of reactivating latent virus68US 6,225,048 B1Oregon Health Sciences University · 2001
- Method for inducing monocytes to exhibit the phenotype of activated myeloid dendritic cells32US 6,010,905 AThe United States of America as represented by the Department of Health and Human Services · 2000
- Mixed cell populations for tissue repair and separation technique for cell processing27US 8,158,122 B2Aastrom Biosciences, Inc. · 2012