C07K 14/70539
Mhc-molecules
Official title: {MHC-molecules, e.g. HLA-molecules}
C07K14/70539 (Mhc-molecules) appears on 1,276 US grants and 2,256 published applications in this corpus.
Search patents in C07K- Granted patents
- 1,276
- Published applications
- 2,256
- Assignees
- 682
- Inventors
- 2,867
- Latest grant
- 6 Oct 2026
Filings by year
| Year | Granted patents | Published applications |
|---|---|---|
| 1986 | 1 | 0 |
| 1987 | 0 | 0 |
| 1988 | 0 | 0 |
| 1989 | 0 | 0 |
| 1990 | 0 | 0 |
| 1991 | 2 | 0 |
| 1992 | 4 | 0 |
| 1993 | 2 | 0 |
| 1994 | 4 | 0 |
| 1995 | 6 | 0 |
| 1996 | 20 | 0 |
| 1997 | 22 | 0 |
| 1998 | 27 | 0 |
| 1999 | 31 | 0 |
| 2000 | 34 | 0 |
| 2001 | 31 | 3 |
| 2002 | 22 | 40 |
| 2003 | 20 | 53 |
| 2004 | 14 | 40 |
| 2005 | 12 | 35 |
| 2006 | 18 | 27 |
| 2007 | 15 | 21 |
| 2008 | 11 | 25 |
| 2009 | 8 | 21 |
| 2010 | 8 | 24 |
| 2011 | 9 | 26 |
| 2012 | 13 | 32 |
| 2013 | 8 | 25 |
| 2014 | 21 | 27 |
| 2015 | 14 | 35 |
| 2016 | 18 | 65 |
| 2017 | 17 | 81 |
| 2018 | 63 | 111 |
| 2019 | 110 | 160 |
| 2020 | 108 | 206 |
| 2021 | 121 | 226 |
| 2022 | 116 | 265 |
| 2023 | 102 | 234 |
| 2024 | 118 | 215 |
| 2025 | 88 | 164 |
| 2026 | 38 | 95 |
By publication year. Applications have been published since 2001. 2026 runs to 8 Oct.
Recent patents
- Fusion protein comprising anti-CD3 single domain antibody, exosomal protein CD63 and RNA binding protein, and uses thereof6 Oct 2026US 12,753,232 B1China Medical University Hospital
- T cell receptors specific for a mutant form of the RET oncogene and uses thereof8 Sep 2026US 12,729,370 B2Providence Health & Services - Oregon
- Stabilized MHC I1 Sep 2026US 12,723,068 B2Imusyn GmbH & Co. KG
- Methods and compositions for modulating CAR-T activity25 Aug 2026US 12,715,918 B2Sana Biotechnology, Inc.
- Cell capable of activating immune system, and pharmaceutical composition containing said cell11 Aug 2026US 12,703,867 B2Riken
- Mhc class i molecules8 Oct 2026US 2026/0308228 A1Immudex ApS
- Cd4+ cytotoxic t cells and methods of use thereof8 Oct 2026US 2026/0308522 A1Dana-Farber Cancer Institute, Inc.
- Ligand discovery and gene delivery via retroviral surface display8 Oct 2026US 2026/0309700 A1Massachusetts Institute of Technology
- A t cell receptor recognizing an unmutated foxm1 epitope presented on hla-a*02:011 Oct 2026US 2026/0297157 A1Board of Regents, The University of Texas System
- Hla gene modified cell1 Oct 2026US 2026/0297161 A1Ajinomoto Co., Inc.
Most cited
By later US patents
- Recombinant production of immunoglobulin-like domains in prokaryotic cells477US 6,165,745 ABoard of Regents, The University of Texas System · 2000
- Receptor specific transepithelial transport of therapeutics214US 6,030,613 ABrandeis University · 2000
- HLA typing method and cDNA probes used therein205US 4,582,788 ACetus Corporation · 1986
- Process for detecting specific nucleotide variations and genetic polymorphisms present in nucleic acids160US 5,468,613 AHoffmann-La Roche Inc. · 1995
- Compositions and methods for the detection, quantitation and purification of antigen-specific T cells126US 5,635,363 AThe Board of Trustees of the Leland Stanford Junior University · 1997