C07D 498/22
In which the condensed system contains four or more hetero rings
Official title: in which the condensed system contains four or more hetero rings
C07D498/22 (In which the condensed system contains four or more hetero rings) appears on 568 US grants and 827 published applications in this corpus.
Search patents in C07D- Granted patents
- 568
- Published applications
- 827
- Assignees
- 376
- Inventors
- 2,473
- Latest grant
- 1 Sep 2026
Filings by year
| Year | Granted patents | Published applications |
|---|---|---|
| 1980 | 1 | 0 |
| 1981 | 1 | 0 |
| 1982 | 2 | 0 |
| 1983 | 1 | 0 |
| 1984 | 1 | 0 |
| 1985 | 2 | 0 |
| 1986 | 1 | 0 |
| 1987 | 3 | 0 |
| 1988 | 1 | 0 |
| 1989 | 4 | 0 |
| 1990 | 5 | 0 |
| 1991 | 3 | 0 |
| 1992 | 5 | 0 |
| 1993 | 5 | 0 |
| 1994 | 3 | 0 |
| 1995 | 9 | 0 |
| 1996 | 9 | 0 |
| 1997 | 14 | 0 |
| 1998 | 12 | 0 |
| 1999 | 9 | 0 |
| 2000 | 11 | 0 |
| 2001 | 7 | 0 |
| 2002 | 7 | 10 |
| 2003 | 6 | 6 |
| 2004 | 7 | 6 |
| 2005 | 4 | 6 |
| 2006 | 6 | 8 |
| 2007 | 3 | 14 |
| 2008 | 3 | 16 |
| 2009 | 13 | 26 |
| 2010 | 11 | 20 |
| 2011 | 12 | 23 |
| 2012 | 24 | 43 |
| 2013 | 20 | 27 |
| 2014 | 27 | 36 |
| 2015 | 30 | 38 |
| 2016 | 28 | 47 |
| 2017 | 41 | 52 |
| 2018 | 25 | 19 |
| 2019 | 24 | 29 |
| 2020 | 21 | 40 |
| 2021 | 18 | 44 |
| 2022 | 20 | 53 |
| 2023 | 20 | 69 |
| 2024 | 38 | 70 |
| 2025 | 31 | 71 |
| 2026 | 20 | 54 |
By publication year. Applications have been published since 2001. 2026 runs to 8 Oct.
Recent patents
- Crystal form of compound and use thereof1 Sep 2026US 12,723,050 B2Tennor Therapeutics (Suzhou) Limited
- Crystal form of macrocyclic compound, and preparation method therefor and use thereof4 Aug 2026US 12,698,293 B2Hitgen Inc.
- Tetrahydroisoquinoline derivatives for the treatment of red blood disorders and inflammatory diseases28 Jul 2026US 12,692,274 B2Sanofi
- Aroyl substituted tricyclic compound, preparation method therefor and use thereof28 Jul 2026US 12,692,275 B2Genfleet Therapeutics (Shanghai) Inc.
- Macrocyclic urea orexin receptor agonists21 Jul 2026US 12,686,690 B2Merck Sharp & Dohme Corp.
- Imidazolium salt macrocyclic compound and preparation method therefor and use thereof8 Oct 2026US 2026/0308175 A1Fudan University
- Ras inhibitors1 Oct 2026US 2026/0297112 A1Revolution Medicines, Inc.
- Macrocyclic compounds as usp1 inhibitors24 Sep 2026US 2026/0285876 A1Guangdong Newopp Biopharmaceuticals Co., Ltd.
- Macrocyclic EGFR Inhibitor, and Preparation Method Therefor and Pharmaceutical Use Thereof24 Sep 2026US 2026/0285877 A1Abbisko Therapeutics Co., Ltd.
- Small molecule glp-1 agonists24 Sep 2026US 2026/0285878 A1Ambrosia Biosciences Inc.
Most cited
By later US patents
- Rapamycin oximes and hydrazones110US 5,378,836 AAmerican Home Products Corporation · 1995
- Bicyclic rapamycins107US 5,120,725 AAmerican Home Products Corporation · 1992
- Photocyclized rapamycin88US 6,015,809 AAmerican Home Products Corporation · 2000
- Derivatives of physiologically active substance K-25287US 4,923,986 AKyowa Hakko Kogyo Co., Ltd. · 1990
- Imidazo-rifamycin derivatives with antibacterial utility86US 4,341,785 AAlfa Farmaceutici S.p.A. · 1982