C07D 491/10
Spiro-condensed systems
C07D491/10 (Spiro-condensed systems) appears on 2,662 US grants and 3,202 published applications in this corpus.
Search patents in C07D- Granted patents
- 2,662
- Published applications
- 3,202
- Assignees
- 1,109
- Inventors
- 10,129
- Latest grant
- 6 Oct 2026
Filings by year
| Year | Granted patents | Published applications |
|---|---|---|
| 1976 | 7 | 0 |
| 1977 | 6 | 0 |
| 1978 | 7 | 0 |
| 1979 | 10 | 0 |
| 1980 | 20 | 0 |
| 1981 | 24 | 0 |
| 1982 | 16 | 0 |
| 1983 | 20 | 0 |
| 1984 | 18 | 0 |
| 1985 | 21 | 0 |
| 1986 | 27 | 0 |
| 1987 | 20 | 0 |
| 1988 | 14 | 0 |
| 1989 | 17 | 0 |
| 1990 | 15 | 0 |
| 1991 | 14 | 0 |
| 1992 | 22 | 0 |
| 1993 | 15 | 0 |
| 1994 | 16 | 0 |
| 1995 | 19 | 0 |
| 1996 | 38 | 0 |
| 1997 | 41 | 0 |
| 1998 | 29 | 0 |
| 1999 | 28 | 0 |
| 2000 | 34 | 0 |
| 2001 | 35 | 5 |
| 2002 | 49 | 41 |
| 2003 | 44 | 79 |
| 2004 | 43 | 89 |
| 2005 | 42 | 78 |
| 2006 | 55 | 86 |
| 2007 | 40 | 84 |
| 2008 | 42 | 83 |
| 2009 | 64 | 98 |
| 2010 | 63 | 102 |
| 2011 | 58 | 106 |
| 2012 | 74 | 116 |
| 2013 | 103 | 141 |
| 2014 | 121 | 138 |
| 2015 | 125 | 160 |
| 2016 | 118 | 158 |
| 2017 | 136 | 129 |
| 2018 | 108 | 130 |
| 2019 | 143 | 161 |
| 2020 | 94 | 156 |
| 2021 | 107 | 149 |
| 2022 | 119 | 173 |
| 2023 | 86 | 193 |
| 2024 | 105 | 207 |
| 2025 | 120 | 191 |
| 2026 | 70 | 149 |
By publication year. Applications have been published since 2001. 2026 runs to 8 Oct.
Subgroups
Granted patents
Recent patents
- P38alpha mitogen-activated protein kinase inhibitors6 Oct 2026US 12,753,184 B2Gen1E Lifesciences Inc.
- Pharmaceutical compounds and methods of making and using the same29 Sep 2026US 12,747,208 B2Athos Therapeutics, Inc.
- Triazolyl derivatives as GABAA α5 PAM29 Sep 2026US 12,747,235 B2Hoffmann-La Roche Inc.
- Inhibitors and uses thereof22 Sep 2026US 12,740,991 B2Vividion Therapeutics, Inc.
- Pyrazolyl quinoxaline kinase inhibitors22 Sep 2026US 12,741,956 B2Astex Therapeutics Limited
- 1,3,4-thiadiazol-2-yl carboxamide and 1,3-thiazol-2-yl carboxamide compounds and uses thereof as inhibitors of human polymerase theta1 Oct 2026US 2026/0294921 A1Gilead Sciences, Inc.
- Compounds for the degradation of mutant braf1 Oct 2026US 2026/0297060 A1C4 Therapeutics, Inc.
- Compounds and methods of treating cancers1 Oct 2026US 2026/0297081 A1Cullgen Inc.
- Oxazole trpml1 agonists and uses thereof1 Oct 2026US 2026/0297104 A1Libra Therapeutics, Inc.
- Raf-mek protein complex modulators and methods of use thereof1 Oct 2026US 2026/0297105 A1Gandeeva Therapeutics, Inc.
Most cited
By later US patents
- Urea derivatives and their use as ACAT inhibitors134US 5,621,010 ANisshin Flour Milling Co., Ltd. · 1997
- Cyclic protein tyrosine kinase inhibitors134US 6,596,746 B1Bristol-Myers Squibb Company · 2003
- Thermal imaging method121US 4,720,449 APolaroid Corporation · 1988
- 4-pyrazolyl-N-arylpyrimidin-2-amines and 4-pyrazolyl-N-heteroarylpyrimidin-2-amines as janus kinase inhibitors109US 8,309,718 B2Incyte Corporation · 2012
- Modulators of ATP-binding cassette transporters109US 8,642,609 B2Vertex Pharmaceuticals Incorporated · 2014