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US 12,740,991 B2Granted
Inhibitors and uses thereof
AssigneeVividion Therapeutics, Inc.
InventorsDavid Weinstein, Jason Green, Shota Kikuchi, Donald C Rogness, Philip Alabi, Matthew Patricelli, Nilotpal Roy, I-Chung Lo
Life of this patent
Estimating the term…
Abstract
Compounds and methods for inhibiting Nrf2 by activating KEAP1.
Claims10
A compound of Formula (V), or a pharmaceutically acceptable salt thereof:
- wherein
- X4 is N or CR3;
- and
- R3 is H or D.
1 more element
A compound that is (R)-1-(3-(3-(4-aminopyrimidin-2-yl)-5-chlorophenyl) morpholino) prop-2-en-1-one of formula:
- or a pharmaceutically acceptable salt thereof.
A compound that is (R)-1-(3-(3-(4-amino-1,3,5-triazin-2-yl)-5-chlorophenyl) morpholino) prop-2-en-1-one of formula:
- or a pharmaceutically acceptable salt thereof.
Dependencies are inferred from the claim text.