C07D 477/00
Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a
Official title: Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula: [IMAGE cpc-sch-C07D-0990.gif], e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
C07D477/00 (Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a) appears on 656 US grants and 163 published applications in this corpus.
Search patents in C07D- Granted patents
- 656
- Published applications
- 163
- Assignees
- 130
- Inventors
- 922
- Latest grant
- 12 May 2026
Filings by year
| Year | Granted patents | Published applications |
|---|---|---|
| 1976 | 2 | 0 |
| 1977 | 1 | 0 |
| 1978 | 3 | 0 |
| 1979 | 16 | 0 |
| 1980 | 34 | 0 |
| 1981 | 34 | 0 |
| 1982 | 32 | 0 |
| 1983 | 31 | 0 |
| 1984 | 25 | 0 |
| 1985 | 21 | 0 |
| 1986 | 5 | 0 |
| 1987 | 15 | 0 |
| 1988 | 18 | 0 |
| 1989 | 14 | 0 |
| 1990 | 20 | 0 |
| 1991 | 28 | 0 |
| 1992 | 33 | 0 |
| 1993 | 29 | 0 |
| 1994 | 32 | 0 |
| 1995 | 31 | 0 |
| 1996 | 30 | 0 |
| 1997 | 32 | 0 |
| 1998 | 14 | 0 |
| 1999 | 13 | 0 |
| 2000 | 7 | 0 |
| 2001 | 22 | 5 |
| 2002 | 14 | 7 |
| 2003 | 8 | 9 |
| 2004 | 3 | 14 |
| 2005 | 2 | 4 |
| 2006 | 12 | 10 |
| 2007 | 3 | 6 |
| 2008 | 4 | 6 |
| 2009 | 5 | 12 |
| 2010 | 3 | 10 |
| 2011 | 2 | 13 |
| 2012 | 11 | 6 |
| 2013 | 3 | 9 |
| 2014 | 4 | 2 |
| 2015 | 7 | 8 |
| 2016 | 6 | 3 |
| 2017 | 3 | 6 |
| 2018 | 4 | 3 |
| 2019 | 3 | 2 |
| 2020 | 3 | 7 |
| 2021 | 4 | 5 |
| 2022 | 1 | 2 |
| 2023 | 3 | 3 |
| 2024 | 2 | 7 |
| 2025 | 2 | 3 |
| 2026 | 2 | 1 |
By publication year. Applications have been published since 2001. 2026 runs to 8 Oct.
Subgroups
Granted patents
Recent patents
- Beta-lactam compounds and methods of use thereof12 May 2026US 12,624,382 B2The University of Hong Kong
- 2,5-disubstituted 3-methyl pyrazines and 2,5,6-trisubstituted 3-methyl pyrazines as allosteric SHP2 inhibitors3 Mar 2026US 12,565,476 B2Revolution Medicines, Inc.
- Continuous post-treatment method and device for penem compound20 May 2025US 12,303,805 B2Asymchem Laboratories (Tianjin) Co., Ltd.
- β-lactam-cannabinoid conjugate molecules25 Mar 2025US 12,257,307 B2Diverse Biotech, Inc.
- Tebipenem pivoxil crystalline forms, compositions including the same, methods of manufacture, and methods of use24 Sep 2024US 12,098,155 B2Spero Therapeutics, Inc.
- Tebipenem pivoxil crystalline forms, compositions including the same, methods of manufacture, and methods of use9 Jul 2026US 2026/0193262 A1Spero Therapeutics, Inc.
- Beta-Lactam-Cannabinoid Conjugate Molecules10 Jul 2025US 2025/0222118 A1Diverse Biotech, Inc.
- Tebipenem pivoxil crystalline forms, compositions including the same, methods of manufacture, and methods of use13 Feb 2025US 2025/0051334 A1Spero Therapeutics, Inc.
- New crystal form of ertapenem sodium and preparation method therefor30 Jan 2025US 2025/0034144 A1Asymchem Laboratories (Tianjin) Co., Ltd.
- Modified carbapenem antibiotics with improved activity against kpc carbapenemase-producing enterobacterales21 Nov 2024US 2024/0383899 A1Southern Methodist University
Most cited
By later US patents
- Antibiotics121US 3,950,357 AMerck & Co., Inc. · 1976
- Substituted N-methylene derivatives of thienamycin78US 4,194,047 AMerck & Co., Inc. · 1980
- 1-, 6- And 2-substituted-1-carba-2-penem-3-carboxylic acids72US 4,260,627 AMerck & Co., Inc. · 1981
- 2-(Heterocyclylalkyl)phenyl carbapenem antibacterial agents66US 4,962,101 AMerck & Co., Inc. · 1990
- Carbapenem compound in crystalline form, and its production and use56US 4,888,344 ASumitomo Pharmaceuticals Company, Limited · 1989