C07D 257/08
Six-membered rings
C07D257/08 (Six-membered rings) appears on 73 US grants and 97 published applications in this corpus.
Search patents in C07D- Granted patents
- 73
- Published applications
- 97
- Assignees
- 63
- Inventors
- 240
- Latest grant
- 7 Jul 2026
Filings by year
| Year | Granted patents | Published applications |
|---|---|---|
| 1979 | 1 | 0 |
| 1980 | 1 | 0 |
| 1981 | 0 | 0 |
| 1982 | 0 | 0 |
| 1983 | 0 | 0 |
| 1984 | 0 | 0 |
| 1985 | 0 | 0 |
| 1986 | 1 | 0 |
| 1987 | 0 | 0 |
| 1988 | 0 | 0 |
| 1989 | 1 | 0 |
| 1990 | 2 | 0 |
| 1991 | 2 | 0 |
| 1992 | 0 | 0 |
| 1993 | 0 | 0 |
| 1994 | 1 | 0 |
| 1995 | 2 | 0 |
| 1996 | 1 | 0 |
| 1997 | 0 | 0 |
| 1998 | 0 | 0 |
| 1999 | 1 | 0 |
| 2000 | 0 | 0 |
| 2001 | 0 | 0 |
| 2002 | 1 | 0 |
| 2003 | 1 | 0 |
| 2004 | 0 | 1 |
| 2005 | 0 | 0 |
| 2006 | 0 | 1 |
| 2007 | 0 | 0 |
| 2008 | 1 | 0 |
| 2009 | 1 | 1 |
| 2010 | 0 | 2 |
| 2011 | 0 | 0 |
| 2012 | 1 | 2 |
| 2013 | 1 | 3 |
| 2014 | 2 | 6 |
| 2015 | 1 | 6 |
| 2016 | 2 | 10 |
| 2017 | 6 | 5 |
| 2018 | 12 | 8 |
| 2019 | 6 | 10 |
| 2020 | 8 | 6 |
| 2021 | 5 | 6 |
| 2022 | 0 | 6 |
| 2023 | 4 | 8 |
| 2024 | 4 | 10 |
| 2025 | 3 | 5 |
| 2026 | 1 | 1 |
By publication year. Applications have been published since 2001. 2026 runs to 8 Oct.
Recent patents
- Tetrazine compounds for in vivo imaging7 Jul 2026US 12,673,926 B2Københavns Universitet
- TCO conjugates and methods for delivery of therapeutic agents25 Mar 2025US 12,257,326 B2The Regents of the University of California
- 18F-labeled novel tetrazines imaging probes for pretargeting in PET imaging18 Feb 2025US 12,226,495 B2Københavns Universitet
- Cleavable tetrazine used in bio-orthogonal drug activation7 Jan 2025US 12,186,405 B2Tagworks Pharmaceuticals B.V.
- Reagents and methods for bioorthogonal labeling of biomolecules in living cells17 Sep 2024US 12,091,391 B2Oregon State University
- Reagents and methods for bioorthogonal labeling of biomolecules in living cells29 Jan 2026US 2026/0028320 A1Oregon State University
- Biomolecule-polymer-pharmaceutical agent conjugates for delivering the pharmaceutical agent31 Jul 2025US 2025/0243159 A9Massachusetts Institute of Technology
- Method for providing a labeled single isomeric chemical entity targeting vector based on the use of an isomer-free dienophile26 Jun 2025US 2025/0205374 A1University of Copenhagen
- Light-controlled bioorthogonal tetrazine ligation12 Jun 2025US 2025/0188065 A1The Regents of the University of California
- Hydrophilic tetrazine-functionalized payloads for preparation of targeting conjugates1 May 2025US 2025/0135011 A1
Most cited
By later US patents
- Fungicides36US 5,021,581 AImperial Chemical Industries PLC · 1991
- Bodipy dyes for biological imaging30US 10,005,793 B2The General Hospital Corporation · 2018
- Bio-orthogonal drug activation27US 9,421,274 B2Koninklijke Philips N. V. · 2016
- Enzymatic conjugation of antibodies23US 9,764,038 B2Innate Pharma · 2017
- Modified amino acids comprising tetrazine functional groups, methods of preparation, and methods of their use20US 9,840,493 B2Sutro Biopharma, Inc. · 2017