C07D 239/553
With halogen atoms or nitro radicals directly attached to ring carbon atoms
Official title: with halogen atoms or nitro radicals directly attached to ring carbon atoms, e.g. fluorouracil
C07D239/553 (With halogen atoms or nitro radicals directly attached to ring carbon atoms) appears on 198 US grants and 112 published applications in this corpus.
Search patents in C07D- Granted patents
- 198
- Published applications
- 112
- Assignees
- 136
- Inventors
- 552
- Latest grant
- 8 Sep 2026
Filings by year
| Year | Granted patents | Published applications |
|---|---|---|
| 1976 | 5 | 0 |
| 1977 | 5 | 0 |
| 1978 | 8 | 0 |
| 1979 | 0 | 0 |
| 1980 | 2 | 0 |
| 1981 | 3 | 0 |
| 1982 | 5 | 0 |
| 1983 | 4 | 0 |
| 1984 | 3 | 0 |
| 1985 | 6 | 0 |
| 1986 | 6 | 0 |
| 1987 | 5 | 0 |
| 1988 | 7 | 0 |
| 1989 | 10 | 0 |
| 1990 | 6 | 0 |
| 1991 | 7 | 0 |
| 1992 | 10 | 0 |
| 1993 | 4 | 0 |
| 1994 | 3 | 0 |
| 1995 | 4 | 0 |
| 1996 | 3 | 0 |
| 1997 | 3 | 0 |
| 1998 | 3 | 0 |
| 1999 | 1 | 0 |
| 2000 | 3 | 0 |
| 2001 | 8 | 0 |
| 2002 | 5 | 4 |
| 2003 | 2 | 4 |
| 2004 | 1 | 3 |
| 2005 | 1 | 5 |
| 2006 | 2 | 3 |
| 2007 | 2 | 4 |
| 2008 | 2 | 5 |
| 2009 | 2 | 4 |
| 2010 | 1 | 3 |
| 2011 | 3 | 4 |
| 2012 | 6 | 3 |
| 2013 | 3 | 6 |
| 2014 | 5 | 5 |
| 2015 | 5 | 8 |
| 2016 | 7 | 7 |
| 2017 | 4 | 6 |
| 2018 | 6 | 6 |
| 2019 | 2 | 4 |
| 2020 | 3 | 4 |
| 2021 | 0 | 4 |
| 2022 | 5 | 12 |
| 2023 | 2 | 2 |
| 2024 | 4 | 2 |
| 2025 | 0 | 2 |
| 2026 | 1 | 2 |
By publication year. Applications have been published since 2001. 2026 runs to 8 Oct.
Recent patents
- Prodrugs for sustained releasing therapeutic agents and uses thereof8 Sep 2026US 12,729,186 B2Liangjiang Medicine Co., Ltd.
- Pyrimidinedione compounds23 Jul 2024US RE50,050 E1MyoKardia, Inc.
- Conjugates and methods of using the same4 Jun 2024US 11,998,610 B2Flagship Pioneering Innovations V, Inc.
- Composition of 5-fluorouracil and refining method therefor9 Jan 2024US 11,866,413 B2Shanghai Xudong Haipu Pharmaceutical Co., Ltd
- 3-((R)-2-(amino-2-phenylethyl)-1-(2-fluoro-6 trifluoromethyl benzyl)-5-iodo-6-methyl-1H-pyrimidine-2,4-dione or a salt thereof, process for its preparation, and its use in the synthesis of elagolix2 Jan 2024US 11,858,901 B2Moehs Iberica, S.L.
- Anticancer drug conjugates4 Jun 2026US 2026/0151413 A1Ariel Scientific Innovations Ltd.
- Nucleoside derivative for preventing and treating inflammation and application thereof26 Mar 2026US 2026/0083743 A1West China Hospital, Sichuan University
- Heterocyclic compound, preparation method therefor, and use thereof12 Jun 2025US 2025/0188042 A1Sichuan University
- Multi-substituted uracil derivative and preparation method therefor and application thereof27 Feb 2025US 2025/0066310 A1Hangzhou Adamerck Pharmlabs Inc.
- Conjugates and methods of using the same5 Dec 2024US 2024/0398966 A1Flagship Pioneering Innovations V, Inc.
Most cited
By later US patents
- 5-Fluorouracil derivatives103US 4,336,381 AShionogi & Co., Ltd. · 1982
- 3-Aryluracils having an ether (thio) carbomyloxy or sulphomyloxy substituent on the aromatic moiety66US 4,859,229 AHoffmann-La Roche Inc. · 1989
- Pyrimidine or triazine derivatives and herbicides58US 5,527,763 AIhara Chemical Industry Co., Ltd. · 1996
- Aminomethyl derivatives of biologically active substances, and enhanced delivery thereof across topical membranes46US 4,845,081 AUniversity of Florida · 1989
- Conjugate having a cleavable linkage for use in a liposome41US 6,365,179 B1Alza Corporation · 2002