C07D 221/28
Morphinans
C07D221/28 (Morphinans) appears on 175 US grants and 161 published applications in this corpus.
Search patents in C07D- Granted patents
- 175
- Published applications
- 161
- Assignees
- 92
- Inventors
- 286
- Latest grant
- 23 Jun 2026
Filings by year
| Year | Granted patents | Published applications |
|---|---|---|
| 1976 | 1 | 0 |
| 1977 | 5 | 0 |
| 1978 | 4 | 0 |
| 1979 | 5 | 0 |
| 1980 | 6 | 0 |
| 1981 | 7 | 0 |
| 1982 | 1 | 0 |
| 1983 | 7 | 0 |
| 1984 | 2 | 0 |
| 1985 | 2 | 0 |
| 1986 | 1 | 0 |
| 1987 | 1 | 0 |
| 1988 | 3 | 0 |
| 1989 | 0 | 0 |
| 1990 | 1 | 0 |
| 1991 | 1 | 0 |
| 1992 | 0 | 0 |
| 1993 | 1 | 0 |
| 1994 | 0 | 0 |
| 1995 | 0 | 0 |
| 1996 | 1 | 0 |
| 1997 | 1 | 0 |
| 1998 | 1 | 0 |
| 1999 | 1 | 0 |
| 2000 | 0 | 0 |
| 2001 | 1 | 1 |
| 2002 | 2 | 0 |
| 2003 | 1 | 3 |
| 2004 | 1 | 2 |
| 2005 | 2 | 3 |
| 2006 | 1 | 3 |
| 2007 | 3 | 3 |
| 2008 | 1 | 6 |
| 2009 | 2 | 4 |
| 2010 | 2 | 5 |
| 2011 | 6 | 12 |
| 2012 | 6 | 9 |
| 2013 | 8 | 6 |
| 2014 | 10 | 9 |
| 2015 | 7 | 11 |
| 2016 | 10 | 10 |
| 2017 | 7 | 7 |
| 2018 | 5 | 7 |
| 2019 | 7 | 7 |
| 2020 | 12 | 12 |
| 2021 | 3 | 12 |
| 2022 | 9 | 7 |
| 2023 | 4 | 4 |
| 2024 | 4 | 10 |
| 2025 | 5 | 5 |
| 2026 | 4 | 3 |
By publication year. Applications have been published since 2001. 2026 runs to 8 Oct.
Recent patents
- Dextrorphan prodrugs and processes for making and using them23 Jun 2026US 12,662,456 B2Zevra Therapeutics, Inc.
- Opioid receptor antagonists2 Jun 2026US 12,643,907 B2University of Southern California
- Method for introducing deuterated lower alkyl into amine moiety of compound containing secondary amine19 May 2026US 12,630,487 B2Otsuka Pharmaceutical Co., Ltd.
- Levorphanol prodrugs and processes for making and using them31 Mar 2026US 12,590,065 B2Zevra Therapeutics, Inc.
- Non-cryogenic, ammonia-free reduction of aryl compounds23 Sep 2025US 12,421,178 B2University of Pittsburgh—Of the Commonwealth System of Higher Education
- Levorphanol prodrugs and processes for making and using them10 Sep 2026US 2026/0265201 A1Zevra Therapeutics, Inc.
- Methods of producing morphinan alkaloids and derivatives27 Aug 2026US 2026/0250729 A1Antheia, Inc.
- Stereoisomer Conjugates of Dextrorphan9 Apr 2026US 2026/0098013 A1Zevra Therapeutics, Inc.
- A bicyclopentyl thianthrenium compound, process for preparing the same and the use thereof25 Dec 2025US 2025/0388561 A1Studiengesellschaft Kohle gGmbH
- Novel intermediate, method for preparing the same and application thereof16 Oct 2025US 2025/0320221 A1Sichuan University
Most cited
By later US patents
- Morphinan compounds151US 7,973,049 B2Concert Pharmaceuticals, Inc. · 2011
- Morphinan compounds142US 8,188,110 B2Concert Pharmaceuticals, Inc. · 2012
- Morphinan compounds140US 8,541,436 B2Concert Pharmaceuticals, Inc. · 2013
- Dextromethorphan hydrochloride137US 8,017,623 B2Trinity Laboratories, Inc. · 2011
- Substituted benzoate ester prodrug derivatives of 3-hydroxymorphinans, which are analgesics or narcotic antagonists70US 4,668,685 AE. I. Du Pont de Nemours and Company · 1987