C07C 2603/46
1,4,4a,5,5a,6,11,12a- octahydronaphthacenes
Official title: 1,4,4a,5,5a,6,11,12a- Octahydronaphthacenes, e.g. tetracyclines
C07C2603/46 (1,4,4a,5,5a,6,11,12a- octahydronaphthacenes) appears on 143 US grants and 169 published applications in this corpus.
Search patents in C07C- Granted patents
- 143
- Published applications
- 169
- Assignees
- 52
- Inventors
- 245
- Latest grant
- 29 Sep 2026
Filings by year
| Year | Granted patents | Published applications |
|---|---|---|
| 1976 | 4 | 0 |
| 1977 | 1 | 0 |
| 1978 | 1 | 0 |
| 1979 | 0 | 0 |
| 1980 | 0 | 0 |
| 1981 | 0 | 0 |
| 1982 | 0 | 0 |
| 1983 | 0 | 0 |
| 1984 | 0 | 0 |
| 1985 | 0 | 0 |
| 1986 | 0 | 0 |
| 1987 | 0 | 0 |
| 1988 | 0 | 0 |
| 1989 | 0 | 0 |
| 1990 | 3 | 0 |
| 1991 | 4 | 0 |
| 1992 | 0 | 0 |
| 1993 | 1 | 0 |
| 1994 | 4 | 0 |
| 1995 | 10 | 0 |
| 1996 | 10 | 0 |
| 1997 | 2 | 0 |
| 1998 | 1 | 0 |
| 1999 | 1 | 0 |
| 2000 | 2 | 0 |
| 2001 | 0 | 0 |
| 2002 | 1 | 7 |
| 2003 | 4 | 4 |
| 2004 | 4 | 12 |
| 2005 | 4 | 13 |
| 2006 | 2 | 10 |
| 2007 | 3 | 13 |
| 2008 | 4 | 9 |
| 2009 | 3 | 8 |
| 2010 | 11 | 15 |
| 2011 | 4 | 7 |
| 2012 | 14 | 9 |
| 2013 | 9 | 10 |
| 2014 | 1 | 5 |
| 2015 | 6 | 5 |
| 2016 | 9 | 8 |
| 2017 | 6 | 8 |
| 2018 | 4 | 2 |
| 2019 | 1 | 3 |
| 2020 | 1 | 1 |
| 2021 | 0 | 6 |
| 2022 | 0 | 1 |
| 2023 | 2 | 6 |
| 2024 | 0 | 1 |
| 2025 | 4 | 2 |
| 2026 | 2 | 4 |
By publication year. Applications have been published since 2001. 2026 runs to 8 Oct.
Recent patents
- Tetracycline derivatives for treating neurodegenerative or neuroinflammatory diseases29 Sep 2026US 12,746,247 B2Institut Du Cerveau Et De La Moelle Epiniere
- Tetracycline complexes with sustained activity3 Feb 2026US 12,539,333 B2Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e. V.
- Modified tetracyclines for treatment of alcohol use disorder, pain and other disorders involving potential inflammatory processes2 Dec 2025US 12,486,219 B2Texas Tech University System
- Process for making sarecycline hydrochloride13 May 2025US 12,297,161 B2Almirall, S.A.
- Iron catalyzed highly enantioselective cis-dihydroxylation of quinones22 Apr 2025US 12,281,065 B2Laboratory for Synthetic Chemistry and Chemical Biology Limited
- Methods for synthesizing and purifying aminoalkyl tetracycline compounds7 May 2026US 2026/0125341 A1Paratek Pharmaceuticals, Inc.
- Modified Tetracyclines for Treatment of Alcohol Use Disorder, Pain and Other Disorders Involving Potential Inflammatory Processes16 Apr 2026US 2026/0103439 A1Texas Tech University System
- Salts and polymorphs of a tetracycline compound26 Feb 2026US 2026/0053824 A1Paratek Pharmaceuticals, Inc.
- Substituted tetracycline compounds for treatment of inflammatory skin disorders15 Jan 2026US 2026/0015317 A1Paratek Pharmaceuticals, Inc.
- Substituted tetracycline compounds25 Dec 2025US 2025/0388531 A1Paratek Pharmaceuticals, Inc.
Most cited
By later US patents
- 9- (substituted amino) -alpha-6-deoxy-5-oxy tetracycline derivatives, their preparation and their use as antibiotics89US 5,834,450 APfizer Inc. · 1998
- 7, 9-substituted tetracycline compounds85US 6,683,068 B2Paratek Pharmaceuticals, Inc. · 2004
- 7-substituted tetracycline compounds84US 6,818,635 B2Paratek Pharmaceuticals, Inc. · 2004
- 9-substituted minocycline compounds83US 6,846,939 B2Paratek Pharmaceuticals, Inc. · 2005
- Salts of tetracyclines80US 5,538,954 AA/S Dumex (Dumex Ltd.) · 1996