A61K 47/65
Peptidic linkers, binders or spacers
Official title: Peptidic linkers, binders or spacers, e.g. peptidic enzyme-labile linkers
A61K47/65 (Peptidic linkers, binders or spacers) appears on 1,123 US grants and 2,008 published applications in this corpus.
Search patents in A61K- Granted patents
- 1,123
- Published applications
- 2,008
- Assignees
- 862
- Inventors
- 3,920
- Latest grant
- 6 Oct 2026
Filings by year
| Year | Granted patents | Published applications |
|---|---|---|
| 1980 | 1 | 0 |
| 1981 | 1 | 0 |
| 1982 | 1 | 0 |
| 1983 | 1 | 0 |
| 1984 | 0 | 0 |
| 1985 | 0 | 0 |
| 1986 | 0 | 0 |
| 1987 | 2 | 0 |
| 1988 | 0 | 0 |
| 1989 | 2 | 0 |
| 1990 | 0 | 0 |
| 1991 | 3 | 0 |
| 1992 | 6 | 0 |
| 1993 | 1 | 0 |
| 1994 | 4 | 0 |
| 1995 | 0 | 0 |
| 1996 | 3 | 0 |
| 1997 | 4 | 0 |
| 1998 | 4 | 0 |
| 1999 | 7 | 0 |
| 2000 | 5 | 0 |
| 2001 | 7 | 1 |
| 2002 | 12 | 27 |
| 2003 | 16 | 37 |
| 2004 | 16 | 47 |
| 2005 | 13 | 27 |
| 2006 | 18 | 31 |
| 2007 | 14 | 27 |
| 2008 | 13 | 34 |
| 2009 | 20 | 37 |
| 2010 | 22 | 52 |
| 2011 | 21 | 34 |
| 2012 | 20 | 44 |
| 2013 | 29 | 49 |
| 2014 | 32 | 62 |
| 2015 | 40 | 58 |
| 2016 | 47 | 84 |
| 2017 | 45 | 74 |
| 2018 | 53 | 90 |
| 2019 | 50 | 165 |
| 2020 | 79 | 147 |
| 2021 | 82 | 160 |
| 2022 | 86 | 148 |
| 2023 | 106 | 164 |
| 2024 | 105 | 189 |
| 2025 | 87 | 121 |
| 2026 | 45 | 99 |
By publication year. Applications have been published since 2001. 2026 runs to 8 Oct.
Recent patents
- Antibody conjugates and uses thereof6 Oct 2026US 12,753,242 B2GlycoNex Inc.
- Compositions and methods for targeted amplification of coagulation and phagocytosis15 Sep 2026US 12,734,247 B2Case Western Reserve University
- Compositions including multi-agonist peptides and methods of manufacture and use15 Sep 2026US 12,735,457 B2Pep2Tango Therapeutics Inc.
- Anti-CEA antibody-exatecan analog conjugate and pharmaceutical use thereof8 Sep 2026US 12,728,168 B2Jiangsu Hengrui Medicine Co., Ltd.
- Artificial antigen presenting cells for genetic engineering of immune cells8 Sep 2026US 12,729,232 B2H. Lee Moffitt Cancer Center and Research Institute, Inc.
- Photodynamic therapy composition24 Sep 2026US 2026/0284194 A1
- Cleavable polymer drug conjugates24 Sep 2026US 2026/0284196 A1Rs Arastirma Egitim Danismanlik Ilac Sanayi Ticaret Anonim Sirketi
- Cleavable polymer drug conjugates24 Sep 2026US 2026/0284197 A1Rs Arstirma Egitim Danismanlik Ilac Sanayi Ticaret Anonim Sirketi
- Compositions and methods for treating tendon and bone injuries24 Sep 2026US 2026/0284201 A1The Regents of the University of California
- Immune inducer containing polynucleotide-peptide conjugate and pharmaceutical composition containing same24 Sep 2026US 2026/0284210 A1Daiichi Sankyo Company, Limited
Most cited
By later US patents
- N-maleimidyl polymer derivatives171US 6,602,498 B2Shearwater Corporation · 2003
- Heterocyclic self-immolative linkers and conjugates164US 7,375,078 B2Genentech, Inc. · 2008
- Albumin fusion proteins157US 6,905,688 B2Human Genome Sciences, Inc. · 2005
- Elongated and multiple spacers in activatible prodrugs154US 7,223,837 B2Syntarga B.V. · 2007
- Covalent lipid-drug conjugates for drug targeting152US 5,149,794 AState of Oregon · 1992