A61K 35/407
Liver
Official title: Liver; Hepatocytes
A61K35/407 (Liver) appears on 297 US grants and 564 published applications in this corpus.
Search patents in A61K- Granted patents
- 297
- Published applications
- 564
- Assignees
- 296
- Inventors
- 985
- Latest grant
- 15 Sep 2026
Filings by year
| Year | Granted patents | Published applications |
|---|---|---|
| 1979 | 1 | 0 |
| 1980 | 0 | 0 |
| 1981 | 2 | 0 |
| 1982 | 1 | 0 |
| 1983 | 1 | 0 |
| 1984 | 3 | 0 |
| 1985 | 1 | 0 |
| 1986 | 1 | 0 |
| 1987 | 1 | 0 |
| 1988 | 1 | 0 |
| 1989 | 2 | 0 |
| 1990 | 1 | 0 |
| 1991 | 1 | 0 |
| 1992 | 0 | 0 |
| 1993 | 0 | 0 |
| 1994 | 4 | 0 |
| 1995 | 0 | 0 |
| 1996 | 1 | 0 |
| 1997 | 2 | 0 |
| 1998 | 8 | 0 |
| 1999 | 6 | 0 |
| 2000 | 3 | 0 |
| 2001 | 4 | 2 |
| 2002 | 4 | 2 |
| 2003 | 1 | 6 |
| 2004 | 3 | 11 |
| 2005 | 4 | 5 |
| 2006 | 1 | 10 |
| 2007 | 2 | 12 |
| 2008 | 0 | 10 |
| 2009 | 1 | 7 |
| 2010 | 2 | 12 |
| 2011 | 9 | 16 |
| 2012 | 3 | 15 |
| 2013 | 7 | 27 |
| 2014 | 19 | 33 |
| 2015 | 21 | 41 |
| 2016 | 14 | 31 |
| 2017 | 17 | 31 |
| 2018 | 14 | 31 |
| 2019 | 18 | 39 |
| 2020 | 13 | 34 |
| 2021 | 18 | 36 |
| 2022 | 13 | 40 |
| 2023 | 13 | 33 |
| 2024 | 24 | 31 |
| 2025 | 20 | 30 |
| 2026 | 12 | 19 |
By publication year. Applications have been published since 2001. 2026 runs to 8 Oct.
Recent patents
- Generation of uniform hepatocytes from human embryonic stem cells by inhibiting TGF-beta and methods of maintaining hepatic cultures15 Sep 2026US 12,734,197 B2Wisconsin Alumni Research Foundation
- Methods of treating erythropoietic protoporphyria, x-linked protoporphyria, or congenital erythropoietic porphyria with glycine transport inhibitors1 Sep 2026US 12,721,847 B2Disc Medicine, Inc.
- Method for expanding hepatocyte in vitro and application1 Sep 2026US 12,723,235 B2Center for Excellence In Molecular Cell Science, Chinese Academy of Sciences
- Isolated adult cells, artificial organs, rehabilitated organs, research tools, organ encasements, organ perfusion systems, and methods for preparing and utilizing the same28 Jul 2026US 12,692,480 B2Massachusetts Institute of Technology
- Encapsulated liver tissue16 Jun 2026US 12,655,392 B2Morphocell Technologies Inc.
- Liver organoids with intrahepatic sympathetic nerves and methods of use thereof17 Sep 2026US 2026/0275295 A1Children's Hospital Medical Center
- Use of regeneration factors in organ transplantation3 Sep 2026US 2026/0256132 A1Altos Labs, Inc.
- Compositions of secretory and/or catalytic cells and methods using the same3 Sep 2026US 2026/0256846 A1Flagship Pioneering Innovations VI, LLC
- Compositions and methods for treating alpha-1 antitrypsin deficiency3 Sep 2026US 2026/0256848 A1Beam Therapeutics Inc.
- Liver disease regulatory formulation and use thereof27 Aug 2026US 2026/0248860 A1Shanghai Celliver Biotechnology Co., Ltd.
Most cited
By later US patents
- Microcapsules containing viable tissue cells318US 4,391,909 ADamon Corporation · 1983
- Biomaterial derived from vertebrate liver tissue153US 6,379,710 B1Purdue Research Foundation · 2002
- Method and system for delivering therapeutic agents152US 5,865,744 A1999
- Microencapsulation of living tissue and cells150US 4,806,355 AConnaught Laboratories Limited · 1989
- Microencapsulation of living tissue and cells126US 4,689,293 AConnaught Laboratories Limited · 1987