A61K 31/535
Having six-membered rings with at least one nitrogen and one oxygen as
Official title: having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
A61K31/535 (Having six-membered rings with at least one nitrogen and one oxygen as) appears on 9,790 US grants and 17,130 published applications in this corpus.
Search patents in A61K- Granted patents
- 9,790
- Published applications
- 17,130
- Assignees
- 4,423
- Inventors
- 32,447
- Latest grant
- 6 Oct 2026
Filings by year
| Year | Granted patents | Published applications |
|---|---|---|
| 1976 | 18 | 0 |
| 1977 | 13 | 0 |
| 1978 | 11 | 0 |
| 1979 | 12 | 0 |
| 1980 | 12 | 0 |
| 1981 | 6 | 0 |
| 1982 | 5 | 0 |
| 1983 | 6 | 0 |
| 1984 | 4 | 0 |
| 1985 | 3 | 0 |
| 1986 | 5 | 0 |
| 1987 | 4 | 0 |
| 1988 | 14 | 0 |
| 1989 | 11 | 0 |
| 1990 | 24 | 0 |
| 1991 | 13 | 0 |
| 1992 | 45 | 0 |
| 1993 | 39 | 0 |
| 1994 | 24 | 0 |
| 1995 | 30 | 0 |
| 1996 | 43 | 0 |
| 1997 | 68 | 0 |
| 1998 | 65 | 0 |
| 1999 | 75 | 0 |
| 2000 | 97 | 0 |
| 2001 | 126 | 42 |
| 2002 | 115 | 167 |
| 2003 | 107 | 257 |
| 2004 | 89 | 260 |
| 2005 | 85 | 267 |
| 2006 | 105 | 307 |
| 2007 | 87 | 295 |
| 2008 | 100 | 276 |
| 2009 | 127 | 340 |
| 2010 | 143 | 414 |
| 2011 | 164 | 459 |
| 2012 | 264 | 480 |
| 2013 | 407 | 775 |
| 2014 | 523 | 1024 |
| 2015 | 666 | 1102 |
| 2016 | 710 | 1092 |
| 2017 | 827 | 1084 |
| 2018 | 704 | 938 |
| 2019 | 699 | 900 |
| 2020 | 592 | 902 |
| 2021 | 513 | 912 |
| 2022 | 452 | 847 |
| 2023 | 372 | 872 |
| 2024 | 417 | 1062 |
| 2025 | 436 | 1140 |
| 2026 | 313 | 916 |
By publication year. Applications have been published since 2001. 2026 runs to 8 Oct.
Subgroups
Granted patents
- A61K 31/53751,4-oxazines8,310
- A61K 31/5365Ortho- or peri-condensed with heterocyclic ring systems323
- A61K 31/5355Non-condensed oxazines and containing further heterocyclic rings256
- A61K 31/536Ortho- or peri-condensed with carbocyclic ring systems253
- A61K 31/537Spiro-condensed or forming part of bridged ring systems211
- A61K 31/5395Having two or more nitrogen atoms in the same ring120
- A61K 31/539Having two or more oxygen atoms in the same ring6
Recent patents
- CDK inhibitors6 Oct 2026US 12,751,951 B2Genentech, Inc.
- Combination therapy of PD-1 axis binding antagonists and LRRK2 inhitibors6 Oct 2026US 12,751,956 B2Hoffmann-La Roche Inc.
- Small molecule inhibitors of viral replication6 Oct 2026US 12,751,963 B2The Trustees of Princeton University
- Compositions and methods of treating lupus nephritis6 Oct 2026US 12,752,005 B2Genentech, Inc.
- PHD inhibitor compounds, compositions, and use6 Oct 2026US 12,753,161 B2Akebia Therapeutics, Inc.
- Drug-containing particle8 Oct 2026US 2026/0306409 A1Towa Pharmaceutical Co., Ltd.
- Inhaled statins as bronchodilators to improve lung function in respiratory diseases8 Oct 2026US 2026/0306477 A1Beth Israel Deaconess Medical Center, Inc.
- Substituted nucleoside analogs as prmt5 inhibitors8 Oct 2026US 2026/0306479 A1Lupin Limited
- Inverse agonists of rar related orphan receptors (rors)8 Oct 2026US 2026/0306484 A111949098 CANADA INC. (NUREDCO) c/o Jean I. TCHERVENKOV
- Pim1 inhibitor for treating myeloproliferative neoplasms8 Oct 2026US 2026/0306490 A1Sumitomo Pharma America, Inc.
Most cited
By later US patents
- Solid carriers for improved delivery of active ingredients in pharmaceutical compositions930US 6,248,363 B1Lipocine Inc. · 2001
- Cytotoxic agents comprising maytansinoids and their therapeutic use805US 5,208,020 AImmunoGen, Inc. · 1993
- Solid carriers for improved delivery of active ingredients in pharmaceutical compositions684US 6,923,988 B2Lipocine Inc. · 2005
- Solid carriers for improved delivery of hydrophobic active ingredients in pharmaceutical compositions616US 6,569,463 B2Lipocine Inc. · 2003
- Cytotoxic agents comprising maytansinoids and their therapeutic use515US 5,416,064 AImmunoGen, Inc. · 1995