A61K 2800/244
Endothermic
Official title: Endothermic; Cooling; Cooling sensation
A61K2800/244 (Endothermic) appears on 247 US grants and 360 published applications in this corpus.
Search patents in A61K- Granted patents
- 247
- Published applications
- 360
- Assignees
- 123
- Inventors
- 775
- Latest grant
- 14 Jul 2026
Filings by year
| Year | Granted patents | Published applications |
|---|---|---|
| 1977 | 8 | 0 |
| 1978 | 3 | 0 |
| 1979 | 8 | 0 |
| 1980 | 4 | 0 |
| 1981 | 5 | 0 |
| 1982 | 1 | 0 |
| 1983 | 0 | 0 |
| 1984 | 0 | 0 |
| 1985 | 0 | 0 |
| 1986 | 1 | 0 |
| 1987 | 1 | 0 |
| 1988 | 0 | 0 |
| 1989 | 1 | 0 |
| 1990 | 0 | 0 |
| 1991 | 0 | 0 |
| 1992 | 2 | 0 |
| 1993 | 1 | 0 |
| 1994 | 1 | 0 |
| 1995 | 2 | 0 |
| 1996 | 0 | 0 |
| 1997 | 5 | 0 |
| 1998 | 8 | 0 |
| 1999 | 3 | 0 |
| 2000 | 7 | 0 |
| 2001 | 10 | 1 |
| 2002 | 4 | 9 |
| 2003 | 7 | 12 |
| 2004 | 3 | 13 |
| 2005 | 6 | 7 |
| 2006 | 5 | 13 |
| 2007 | 2 | 17 |
| 2008 | 2 | 20 |
| 2009 | 4 | 21 |
| 2010 | 4 | 23 |
| 2011 | 10 | 19 |
| 2012 | 11 | 11 |
| 2013 | 13 | 26 |
| 2014 | 14 | 26 |
| 2015 | 7 | 18 |
| 2016 | 14 | 13 |
| 2017 | 13 | 17 |
| 2018 | 10 | 13 |
| 2019 | 11 | 16 |
| 2020 | 5 | 12 |
| 2021 | 12 | 7 |
| 2022 | 4 | 7 |
| 2023 | 3 | 10 |
| 2024 | 4 | 15 |
| 2025 | 5 | 7 |
| 2026 | 3 | 7 |
By publication year. Applications have been published since 2001. 2026 runs to 8 Oct.
Recent patents
- Organic compounds as TRPM8 activators14 Jul 2026US 12,678,386 B2Givaudan SA
- Multifunctional facial patch product10 Mar 2026US 12,569,413 B1Aso LLC
- Substituted azacyles as TRPM8 modulators20 Jan 2026US 12,528,801 B2Givaudan SA
- Compositions, methods, and kits for cleansing and moisturizing21 Oct 2025US 12,447,125 B2Naturally Sensible Solutions, LLC
- Solubilization of poorly soluble cooling substances14 Oct 2025US 12,440,435 B2Symrise AG
- Mixtures and uses of (2e)-3-(1,3-benzodioxol-5-yl)-n-phenyl-n-(tetrahydro-3-furanyl)-2-propenamide27 Aug 2026US 2026/0248704 A1Symrise AG
- Massaging balm formulation20 Aug 2026US 2026/0240767 A1Chattem, Inc.
- Film-based skin care products for topical application13 Aug 2026US 2026/0232544 A1
- Substituted azacyles as trpm8 modulators16 Apr 2026US 2026/0103459 A1Givaudan SA
- Methods of Providing a Cooling Sensation to Skin Afflicted with Eczema12 Mar 2026US 2026/0069552 A1Kenvue Brands LLC
Most cited
By later US patents
- Compositions which have a physiological cooling effect, and active compounds suitable for these compositions241US 5,266,592 AHaarmann & Reimer GmbH · 1993
- P-Menthane carboxamides having a physiological cooling effect171US 4,136,163 AWilkinson Sword Limited · 1979
- Coolant compositions140US 5,451,404 AThe Procter & Gamble Company · 1995
- Foamable aerosol preparation138US 5,352,437 AHisamitsu Pharmaceutical Co., Inc. · 1994
- Cool feeling composition137US 6,328,982 B1Takasago International Corporation · 2001