C40B 10/00
Directed molecular evolution of macromolecules
Official title: Directed molecular evolution of macromolecules, e.g. RNA, DNA or proteins
C40B10/00 (Directed molecular evolution of macromolecules) appears on 42 US grants and 69 published applications in this corpus.
Search patents in C40B- Granted patents
- 42
- Published applications
- 69
- Assignees
- 49
- Inventors
- 131
- Latest grant
- 8 Sep 2026
Filings by year
| Year | Granted patents | Published applications |
|---|---|---|
| 2003 | 1 | 2 |
| 2004 | 0 | 0 |
| 2005 | 1 | 0 |
| 2006 | 0 | 3 |
| 2007 | 0 | 1 |
| 2008 | 1 | 3 |
| 2009 | 0 | 4 |
| 2010 | 1 | 6 |
| 2011 | 1 | 0 |
| 2012 | 1 | 2 |
| 2013 | 1 | 3 |
| 2014 | 3 | 1 |
| 2015 | 1 | 2 |
| 2016 | 1 | 6 |
| 2017 | 1 | 2 |
| 2018 | 3 | 5 |
| 2019 | 5 | 9 |
| 2020 | 3 | 6 |
| 2021 | 4 | 4 |
| 2022 | 3 | 2 |
| 2023 | 3 | 2 |
| 2024 | 3 | 2 |
| 2025 | 3 | 4 |
| 2026 | 2 | 0 |
By publication year. 2026 runs to 8 Oct.
Recent patents
- Methods of producing extracellular vesicles8 Sep 2026US 12,728,098 B2Lonza Sales AG
- Oligonucleotide directed and recorded combinitorial synthesis of encoded probe molecules16 Jun 2026US 12,655,420 B2Insitro, Inc.
- Negative selection and stringency modulation in continuous evolution systems26 Aug 2025US 12,398,390 B2President and Fellows of Harvard College
- Antibody library and method5 Aug 2025US 12,378,696 B2Fusion Antibodies Limited
- Mammalian cell line for protein production and library generation18 Mar 2025US 12,252,690 B2ETH Zurich
- Antibody Library and Method18 Dec 2025US 2025/0382726 A1Fusion Antibodies Limited
- Compositions and methods relating to engineered rna polymerases with capping enzymes11 Sep 2025US 2025/0283060 A1Board of Regents, The University of Texas System
- Biosynthesis of cannabinoids and cannabinoid precursors11 Sep 2025US 2025/0283122 A1Ginkgo Bioworks, Inc.
- Mammalian cell line for protein production and library generation31 Jul 2025US 2025/0243478 A1ETH Zurich
- Activatable antibodies and methods of making and using thereof9 May 2024US 2024/0150749 A1Adagene Inc.
Most cited
By later US patents
- Negative selection and stringency modulation in continuous evolution systems64US 10,179,911 B2President and Fellows of Harvard College · 2019
- Library design in combinatorial chemistry by Monte Carlo methods8US 6,640,191 B1The Regents of the University of California · 2003
- Genetic selection for protein folding and solubility in the bacterial periplasm7US 8,722,584 B2Cornell University · 2014
- Micro-organisms for the production of 1,2-propanediol obtained by a combination of evolution and rational design5US 8,298,807 B2Metabolic Explorer · 2012
- High-throughput immune sequencing2US 10,392,726 B2President and Fellows of Harvard College · 2019