C12N 2310/351
Conjugate
C12N2310/351 (Conjugate) appears on 2,991 US grants and 5,909 published applications in this corpus.
Search patents in C12N- Granted patents
- 2,991
- Published applications
- 5,909
- Assignees
- 1,386
- Inventors
- 7,278
- Latest grant
- 6 Oct 2026
Filings by year
| Year | Granted patents | Published applications |
|---|---|---|
| 1993 | 1 | 0 |
| 1994 | 2 | 0 |
| 1995 | 3 | 0 |
| 1996 | 11 | 0 |
| 1997 | 23 | 0 |
| 1998 | 30 | 0 |
| 1999 | 21 | 0 |
| 2000 | 24 | 0 |
| 2001 | 19 | 6 |
| 2002 | 30 | 22 |
| 2003 | 13 | 63 |
| 2004 | 10 | 60 |
| 2005 | 10 | 68 |
| 2006 | 8 | 95 |
| 2007 | 9 | 64 |
| 2008 | 13 | 62 |
| 2009 | 28 | 122 |
| 2010 | 41 | 118 |
| 2011 | 69 | 142 |
| 2012 | 85 | 145 |
| 2013 | 97 | 142 |
| 2014 | 96 | 175 |
| 2015 | 152 | 252 |
| 2016 | 151 | 320 |
| 2017 | 179 | 267 |
| 2018 | 198 | 338 |
| 2019 | 221 | 343 |
| 2020 | 221 | 358 |
| 2021 | 239 | 430 |
| 2022 | 218 | 438 |
| 2023 | 192 | 484 |
| 2024 | 206 | 547 |
| 2025 | 216 | 514 |
| 2026 | 155 | 334 |
By publication year. Applications have been published since 2001. 2026 runs to 8 Oct.
Subgroups
Granted patents
Recent patents
- CAS12B enzymes and systems6 Oct 2026US 12,753,406 B2Massachusetts Institute of Technology
- Chemically modified oligonucleotides targeting bromodomain containing protein 4 (BRD4) for immunotherapy6 Oct 2026US 12,753,407 B2Phio Pharmaceuticals Corp.
- Double-stranded RNAi agents for targeting and regulating HBV gene expression, and a use thereof6 Oct 2026US 12,753,409 B2Hangzhou Tianlong Pharmaceutical Co., Ltd.
- Riboswitch modulated gene therapy for retinal diseases29 Sep 2026US 12,747,441 B2The Medical College of Wisconsin, Inc.
- Muscle-targeting complexes and uses thereof22 Sep 2026US 12,742,007 B2Dyne Therapeutics, Inc.
- Modulating apolipoprotein (a) expression8 Oct 2026US 2026/0308584 A1Ionis Pharmaceuticals, Inc.
- Treatment of gpam related diseases and disorders8 Oct 2026US 2026/0308594 A1Empirico Inc.
- Methods of minimising effects of smoke exposure8 Oct 2026US 2026/0308597 A1Rage Biotech Pty Ltd
- Nucleic acid-peptide-nucleic acid conjugate molecules and methods of making the same1 Oct 2026US 2026/0295069 A1Arizona Board of Regents on behalf of Arizona State University
- Compositions, systems and methods for programming immune cell function through targeted gene regulation1 Oct 2026US 2026/0297545 A1Duke University
Most cited
By later US patents
- Antisense oligonucleotide modulation of multidrug resistance-associated protein841US 5,801,154 AIsis Pharmaceuticals, Inc. · 1998
- Nucleic acid hybridization and amplification method for detection of specific sequences in which a complementary labeled nucleic acid probe is cleaved663US 5,403,711 AUniversity of Iowa Research Foundation · 1995
- Sugar modified oligonucleotides that detect and modulate gene expression641US 5,670,633 AIsis Pharmaceuticals, Inc. · 1997
- Substituted purines and oligonucleotide cross-linking603US 5,681,941 AIsis Pharmaceuticals, Inc. · 1997
- 2'modified nucleoside and nucleotide compounds599US 5,466,786 AGilead Sciences, Inc. · 1995