C12N 2310/12
Catalytic nucleic acids
Official title: catalytic nucleic acids, e.g. ribozymes
C12N2310/12 (Catalytic nucleic acids) appears on 871 US grants and 1,278 published applications in this corpus.
Search patents in C12N- Granted patents
- 871
- Published applications
- 1,278
- Assignees
- 603
- Inventors
- 2,531
- Latest grant
- 15 Sep 2026
Filings by year
| Year | Granted patents | Published applications |
|---|---|---|
| 1991 | 2 | 0 |
| 1992 | 5 | 0 |
| 1993 | 7 | 0 |
| 1994 | 4 | 0 |
| 1995 | 1 | 0 |
| 1996 | 13 | 0 |
| 1997 | 50 | 0 |
| 1998 | 54 | 0 |
| 1999 | 52 | 0 |
| 2000 | 59 | 0 |
| 2001 | 31 | 4 |
| 2002 | 34 | 29 |
| 2003 | 29 | 94 |
| 2004 | 19 | 51 |
| 2005 | 8 | 76 |
| 2006 | 17 | 28 |
| 2007 | 3 | 27 |
| 2008 | 7 | 23 |
| 2009 | 9 | 36 |
| 2010 | 17 | 29 |
| 2011 | 18 | 27 |
| 2012 | 14 | 15 |
| 2013 | 15 | 31 |
| 2014 | 7 | 19 |
| 2015 | 17 | 53 |
| 2016 | 22 | 52 |
| 2017 | 26 | 34 |
| 2018 | 30 | 58 |
| 2019 | 39 | 85 |
| 2020 | 39 | 70 |
| 2021 | 40 | 83 |
| 2022 | 38 | 66 |
| 2023 | 46 | 89 |
| 2024 | 40 | 86 |
| 2025 | 34 | 72 |
| 2026 | 25 | 41 |
By publication year. Applications have been published since 2001. 2026 runs to 8 Oct.
Subgroups
Granted patents
- C12N 2310/121HammerheadIndexing code335
- C12N 2310/122HairpinIndexing code315
- C12N 2310/127DnazymesIndexing code112
- C12N 2310/124Based on group i or ii intronsIndexing code107
- C12N 2310/123Hepatitis deltaIndexing code79
- C12N 2310/126Involving rnase pIndexing code70
- C12N 2310/128Processing or releasing ribozymeIndexing code23
Recent patents
- Trans-splicing ribozyme specific to ApoE4 RNA and use thereof15 Sep 2026US 12,735,701 B2Rznomics Inc.
- Electrochemical detection nanostructure, systems and uses thereof15 Sep 2026US 12,735,712 B2Auburn University
- RNA molecules, methods of producing circular RNA, and treatment methods15 Sep 2026US 12,737,877 B2Cornell University
- Pharmaceutical composition containing HERES expression inhibitor for preventing or treating squamous cell carcinoma25 Aug 2026US 12,716,066 B2Industry-Academic Cooperation Foundation, Yonsei University
- Hairpin-like oligonucleotide-conjugated spherical nucleic acid11 Aug 2026US 12,702,719 B2Northwestern University
- Artificial martellivirales satellite rnas1 Oct 2026US 2026/0297605 A1Flagship Pioneering Innovations Vii, LLC
- Circular rna and preparation methods thereof24 Sep 2026US 2026/0286358 A1BeOne Medicines I GmbH
- Compositions comprising polyribonucleotides and uses thereof10 Sep 2026US 2026/0263639 A1Flagship Pioneering Innovations VI, LLC
- Rna-directed dna cleavage by the cas9-crrna complex10 Sep 2026US 2026/0265750 A1Vilnius University
- Novel self-cleaving dnazymes and selection process10 Sep 2026US 2026/0265751 A1Technische Universität München
Most cited
By later US patents
- 2'deoxy-2'-alkylnucleotide containing nucleic acid521US 5,627,053 ARibozyme Pharmaceuticals, Inc. · 1997
- RNA ribozyme polymerases, dephosphorylases, restriction endoribonucleases and methods496US 4,987,071 AUniversity Patents, Inc. · 1991
- Enzymatic nucleic acids containing 5'-and/or 3'-cap structures322US 5,998,203 ARibozyme Pharmaceuticals, Inc. · 1999
- Multivalent and multispecific binding proteins, their manufacture and use314US 5,837,242 ACambridge Antibody Technology Limited · 1998
- Tissue-specific and pathogen-specific toxic agents and ribozymes283US 6,271,359 B1MUSC Foundation for Research Development · 2001