C07K 16/462
Igs containing a variable region from one specie and a constant region
Official title: {Igs containing a variable region (Fv) from one specie and a constant region (Fc) from another}
C07K16/462 (Igs containing a variable region from one specie and a constant region) appears on 310 US grants and 390 published applications in this corpus.
Search patents in C07K- Granted patents
- 310
- Published applications
- 390
- Assignees
- 129
- Inventors
- 361
- Latest grant
- 7 Jul 2026
Filings by year
| Year | Granted patents | Published applications |
|---|---|---|
| 1989 | 2 | 0 |
| 1990 | 2 | 0 |
| 1991 | 0 | 0 |
| 1992 | 0 | 0 |
| 1993 | 3 | 0 |
| 1994 | 1 | 0 |
| 1995 | 0 | 0 |
| 1996 | 8 | 0 |
| 1997 | 10 | 0 |
| 1998 | 13 | 0 |
| 1999 | 8 | 0 |
| 2000 | 8 | 0 |
| 2001 | 9 | 0 |
| 2002 | 4 | 3 |
| 2003 | 9 | 8 |
| 2004 | 4 | 5 |
| 2005 | 3 | 13 |
| 2006 | 2 | 6 |
| 2007 | 1 | 7 |
| 2008 | 2 | 2 |
| 2009 | 3 | 11 |
| 2010 | 7 | 11 |
| 2011 | 3 | 17 |
| 2012 | 10 | 16 |
| 2013 | 8 | 29 |
| 2014 | 11 | 35 |
| 2015 | 20 | 36 |
| 2016 | 28 | 24 |
| 2017 | 14 | 28 |
| 2018 | 17 | 28 |
| 2019 | 16 | 12 |
| 2020 | 23 | 23 |
| 2021 | 14 | 20 |
| 2022 | 13 | 19 |
| 2023 | 12 | 13 |
| 2024 | 8 | 10 |
| 2025 | 11 | 10 |
| 2026 | 3 | 4 |
By publication year. Applications have been published since 2001. 2026 runs to 8 Oct.
Recent patents
- Engineered immunoglobulins with altered FcRn binding7 Jul 2026US 12,674,004 B2Universitetet I Oslo
- Methods and compositions for reducing the immunogenicity of chimeric notch receptors5 May 2026US 12,617,825 B2Cell Design Labs, Inc.
- Mice that make heavy chain antibodies10 Feb 2026US 12,543,713 B2Regeneron Pharmaceuticals, Inc.
- Heterodimeric Fc for making fusion proteins and bispecific antibodies14 Oct 2025US 12,441,816 B2Qilu Puget Sound Biotherapeutics Corporation
- Humanized light chain mice7 Oct 2025US 12,433,266 B2Regeneron Pharmaceuticals, Inc.
- Treatment of sjogren's disease with nuclease fusion proteins3 Sep 2026US 2026/0258159 A1Resolve Therapeutics, LLC
- Humanized light chain mice7 May 2026US 2026/0123612 A1Regeneron Pharmaceuticals, Inc.
- Anti-Abeta Antibodies19 Mar 2026US 2026/0078176 A1Othair Prothena Limited
- Non-human animals having an engineered immunoglobulin lambda light chain and uses thereof22 Jan 2026US 2026/0020545 A1Regeneron Pharmaceuticals, Inc.
- Non-human animals expressing exogenous terminal deoxynucleotidyltransferase25 Dec 2025US 2025/0386808 A1Regeneron Pharmaceuticals, Inc.
Most cited
By later US patents
- Recombinant immunoglobin preparations4,785US 4,816,567 AGenentech, Inc. · 1989
- Production of chimeric antibodies - a combinatorial approach1,367US 5,565,332 ACambridge Antibody Technology Limited · 1996
- Multichain polypeptides or proteins and processes for their production1,110US 4,816,397 ACelltech Limited · 1989
- Method of making transgenic mice lacking endogenous heavy chains1,057US 5,939,598 AAbgenix, Inc. · 1999
- Methods for producing members of specific binding pairs893US 5,969,108 ACambridge Antibody Technology Limited · 1999