C07D 251/18
With nitrogen atoms directly attached to the two other ring carbon atoms
Official title: with nitrogen atoms directly attached to the two other ring carbon atoms, e.g. guanamines
C07D251/18 (With nitrogen atoms directly attached to the two other ring carbon atoms) appears on 271 US grants and 200 published applications in this corpus.
Search patents in C07D- Granted patents
- 271
- Published applications
- 200
- Assignees
- 133
- Inventors
- 695
- Latest grant
- 23 Jun 2026
Filings by year
| Year | Granted patents | Published applications |
|---|---|---|
| 1976 | 2 | 0 |
| 1977 | 1 | 0 |
| 1978 | 3 | 0 |
| 1979 | 1 | 0 |
| 1980 | 3 | 0 |
| 1981 | 4 | 0 |
| 1982 | 6 | 0 |
| 1983 | 7 | 0 |
| 1984 | 2 | 0 |
| 1985 | 4 | 0 |
| 1986 | 10 | 0 |
| 1987 | 8 | 0 |
| 1988 | 4 | 0 |
| 1989 | 1 | 0 |
| 1990 | 5 | 0 |
| 1991 | 2 | 0 |
| 1992 | 2 | 0 |
| 1993 | 3 | 0 |
| 1994 | 4 | 0 |
| 1995 | 3 | 0 |
| 1996 | 13 | 0 |
| 1997 | 7 | 0 |
| 1998 | 7 | 0 |
| 1999 | 4 | 0 |
| 2000 | 8 | 0 |
| 2001 | 6 | 2 |
| 2002 | 10 | 4 |
| 2003 | 4 | 15 |
| 2004 | 1 | 10 |
| 2005 | 9 | 10 |
| 2006 | 6 | 5 |
| 2007 | 3 | 7 |
| 2008 | 3 | 5 |
| 2009 | 5 | 9 |
| 2010 | 3 | 12 |
| 2011 | 9 | 9 |
| 2012 | 11 | 7 |
| 2013 | 3 | 10 |
| 2014 | 7 | 5 |
| 2015 | 7 | 9 |
| 2016 | 8 | 9 |
| 2017 | 12 | 19 |
| 2018 | 9 | 3 |
| 2019 | 7 | 11 |
| 2020 | 9 | 7 |
| 2021 | 5 | 6 |
| 2022 | 8 | 7 |
| 2023 | 4 | 3 |
| 2024 | 2 | 6 |
| 2025 | 5 | 9 |
| 2026 | 1 | 1 |
By publication year. Applications have been published since 2001. 2026 runs to 8 Oct.
Recent patents
- Heteroaryl compounds and therapeutic uses thereof in conditions associated with the alteration of the activity of beta-glucocerebrosidase23 Jun 2026US 12,661,342 B2Gt Gain Therapeutics SA
- Therapeutically active compounds and their methods of use7 Oct 2025US 12,433,895 B2Servier Pharmaceuticals LLC
- 2,4,6-trisubstituted 1,3,5-triazines as modulators of CX3CR12 Sep 2025US 12,404,253 B2
- Triazine-based polymer4 Mar 2025US 12,243,664 B2PolyJoule, Inc.
- Cycloolefin substituted heteroaromatic compounds and their use25 Feb 2025US 12,234,211 B2Hutchison Medipharma Limited
- Process for the preparation of biguanidines and triazines23 Jul 2026US 2026/0209186 A1Adama Agan Ltd.
- Process for the preparation of biguanidine salts and triazines18 Dec 2025US 2025/0382262 A1Adama Agan Ltd.
- Crystalline form of indaziflam, methods for its preparation and use thereof18 Dec 2025US 2025/0382272 A1Adama Agan Ltd.
- Process For Preparation of Imeglimin and Salts Thereof13 Nov 2025US 2025/0346566 A1Harman Finochem Limited
- Biologically active compounds and methods thereof2 Oct 2025US 2025/0304571 A1Shanghai Keen Therapeutics Co., Ltd.
Most cited
By later US patents
- 1N-alkyl-N-arylpyrimidinamines and derivatives thereof89US 6,107,301 ADuPont Pharmaceuticals Company · 2000
- 1N-alkyl-n-arylpyrimidinamines and derivatives thereof89US 6,342,503 B12002
- Alkylcarbamylmethylated amino-triazine crosslinking agents and curable compositions containing the same84US 4,710,542 AAmerican Cyanamid Company · 1987
- Heteroaryl, heterocyclic and aryl compounds which inhibit leukocyte adhesion mediated by VLA-4.71US 7,049,306 B2Elan Pharmaceuticals, Inc. · 2006
- Inhibitors of histone deacetylase67US 6,897,220 B2MethylGene Inc. · 2005