A61K 8/4953
Containing pyrimidine ring derivatives
Official title: {containing pyrimidine ring derivatives, e.g. minoxidil}
A61K8/4953 (Containing pyrimidine ring derivatives) appears on 792 US grants and 939 published applications in this corpus.
Search patents in A61K- Granted patents
- 792
- Published applications
- 939
- Assignees
- 358
- Inventors
- 1,747
- Latest grant
- 8 Sep 2026
Filings by year
| Year | Granted patents | Published applications |
|---|---|---|
| 1977 | 4 | 0 |
| 1978 | 3 | 0 |
| 1979 | 2 | 0 |
| 1980 | 3 | 0 |
| 1981 | 1 | 0 |
| 1982 | 1 | 0 |
| 1983 | 2 | 0 |
| 1984 | 0 | 0 |
| 1985 | 4 | 0 |
| 1986 | 2 | 0 |
| 1987 | 1 | 0 |
| 1988 | 2 | 0 |
| 1989 | 9 | 0 |
| 1990 | 12 | 0 |
| 1991 | 17 | 0 |
| 1992 | 11 | 0 |
| 1993 | 10 | 0 |
| 1994 | 11 | 0 |
| 1995 | 16 | 0 |
| 1996 | 36 | 0 |
| 1997 | 55 | 0 |
| 1998 | 18 | 0 |
| 1999 | 18 | 0 |
| 2000 | 12 | 0 |
| 2001 | 12 | 6 |
| 2002 | 20 | 22 |
| 2003 | 15 | 36 |
| 2004 | 14 | 30 |
| 2005 | 9 | 38 |
| 2006 | 17 | 23 |
| 2007 | 11 | 26 |
| 2008 | 10 | 31 |
| 2009 | 8 | 24 |
| 2010 | 13 | 27 |
| 2011 | 10 | 35 |
| 2012 | 12 | 29 |
| 2013 | 16 | 25 |
| 2014 | 12 | 56 |
| 2015 | 37 | 59 |
| 2016 | 43 | 65 |
| 2017 | 48 | 66 |
| 2018 | 33 | 41 |
| 2019 | 28 | 39 |
| 2020 | 29 | 38 |
| 2021 | 38 | 38 |
| 2022 | 25 | 49 |
| 2023 | 30 | 40 |
| 2024 | 23 | 44 |
| 2025 | 17 | 27 |
| 2026 | 12 | 25 |
By publication year. Applications have been published since 2001. 2026 runs to 8 Oct.
Recent patents
- Aqueous oxidative composition comprising xanthine derivatives8 Sep 2026US 12,728,082 B2Kao Corporation
- Eye formulations8 Sep 2026US 12,728,090 B1Bausch + Lomb Ireland Limited
- Process for dyeing keratin materials using a direct dye and an unsaturated heterocyclic salt, and composition comprising same23 Jun 2026US 12,661,312 B2L'oreal
- Aqueous solution for solubilizing salicylic acid, a method for preparation thereof, and a cosmetic composition comprising the same16 Jun 2026US 12,653,767 B2Amorepacific Corporation
- Methods for treating nail brittleness, fragility, or pitting28 Apr 2026US 12,611,408 B2Chemistry RX
- Complex combining a heterocyclic nitrogen biomolecule with a silicic acid, and applications1 Oct 2026US 2026/0294772 A1Exsymol
- Minoxidil adjuvant therapies10 Sep 2026US 2026/0263343 A1Caring Brands, Inc.
- Collaborative care method for scalp hair follicles and strands13 Aug 2026US 2026/0232557 A1Biomedical Research Advisors LLC
- Cosmetic composition comprising niacinamide, a ginger root extract, a carboxylic acrylic polymer, an active agent for combating hair loss and/or an anti-dandruff active agent23 Jul 2026US 2026/0207464 A1L'oreal
- Cosmetic composition comprising 2,4-diaminopyrimidine 3-n-oxide, piroctone olamine, niacinamide, and at least 1% by weight of particular hydroxylated compound16 Jul 2026US 2026/0199210 A1L'oreal
Most cited
By later US patents
- Oxidation hair dye composition containinng diaminopyrazol derivatives and new diaminopyrazol derivatives423US 5,061,289 AWella Aktiengesellschaft · 1991
- Amphoteric compositions and polymeric forms of alpha hydroxyacids, and their therapeutic use354US 5,091,171 A1992
- Oxidation hair dyes based upon tetraaminopyrimidine developers311US 4,003,699 AHenkel & Cie G.m.b.H. · 1977
- Low intensity light therapy for the manipulation of fibroblast, and fibroblast-derived mammalian cells and collagen267US 6,676,655 B2Light BioScience, LLC · 2004
- 6-Amino-4-(substituted amino)-1,2-dihydro-1-hydroxy-2-iminopyrimidine, topical compositions and process for hair growth174US 4,139,619 AThe Upjohn Company · 1979