Low intensity light therapy for the manipulation of fibroblast, and fibroblast-derived mammalian cells and collagen
AssigneeLight BioScience, LLC
InventorDavid H. McDaniel
Life of this patent
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Abstract
Disclosed is a method for treating various dermatalogical conditions using electromagnetic radiation. Particularly preferred are narrowband, multichromatic electromagnetic radiation emitters having a dominant emissive wavelength corresponding to the peak absorption wavelength of the mammalian tissue targetted for treatment. Topical compositions are disclosed for pretreating the targetted tissue to alter the peak absorption wavelength of the tissue.
Claims24
A method for the manipulation of collagen, fibroblast, and fibroblast-derived cell levels in mammalian tissue comprising:
- exposing said tissue to a plurality of pulses from at least one source of narrowband, multichromatic electromagnetic radiation having a dominant emissive wavelength of from about 300 nm to about 1600 nm;
- and
- filtering the source of narrowband, multichromatic electromagnetic radiation to regulate the transmission of infrared radiation to said tissue,
- wherein said pulses have a duration of from about 0.1 femtoseconds to about 100 seconds, the interpulse delay between said pulses is from about 0.1 to about 1000 milliseconds, and the energy fluence received by said tissue is less than about 10 joule per square centimeter and said source of narrowband, multichromatic electromagnetic radiation emits radiation in a bandwidth of about +/−100 nm wound the dominant emissive wavelength.
A method for the manipulation of collagen, fibroblast, and fibroblast-derived cell levels in mammalian tissue comprising:
- exposing said tissue to at least one source of narrowband, multichromatic electromagnetic radiation having a dominant emissive wavelength of from about 300 nm to about 1600 nm for a period of time of from about 10 seconds to about 24 hours, wherein the energy fluence received by said tissue is less than about 10 J/cm2 and said source of narrowband, multichromatic electromagnetic radiation emits radiation in a bandwidth of about +/−100 nm around the dominant emissive wavelength.
A method forte manipulation of collagen, fibroblast, and fibroblast-derived cell levels in mammalian tissue comprising:
- exposing said tissue to at least one source of narrowband, multichromatic electromagnetic radiation having a dominant emissive wavelength of from about 300 nm to about 1600 nm for a period of time of from about 10 seconds to about 24 hours, wherein the energy fluence received by said tissue is less than about 10 J/cm2 and said source of narrowband, multichromatic electromagnetic radiation emits radiation in a bandwidth of about +/−100 nm around the dominant emissive wavelength;
- and
- filtering the source of narrowband, multichromatic electromagnetic radiation to regulate the transmission of infrared radiation to said tissue.
Dependencies are inferred from the claim text.