A61K 31/549
Having two or more nitrogen atoms in the same ring
Official title: having two or more nitrogen atoms in the same ring, e.g. hydrochlorothiazide
A61K31/549 (Having two or more nitrogen atoms in the same ring) appears on 325 US grants and 639 published applications in this corpus.
Search patents in A61K- Granted patents
- 325
- Published applications
- 639
- Assignees
- 292
- Inventors
- 1,094
- Latest grant
- 29 Sep 2026
Filings by year
| Year | Granted patents | Published applications |
|---|---|---|
| 1996 | 3 | 0 |
| 1997 | 0 | 0 |
| 1998 | 1 | 0 |
| 1999 | 4 | 0 |
| 2000 | 7 | 0 |
| 2001 | 6 | 2 |
| 2002 | 9 | 15 |
| 2003 | 8 | 25 |
| 2004 | 9 | 14 |
| 2005 | 4 | 20 |
| 2006 | 9 | 24 |
| 2007 | 1 | 19 |
| 2008 | 3 | 14 |
| 2009 | 6 | 20 |
| 2010 | 3 | 24 |
| 2011 | 11 | 14 |
| 2012 | 8 | 18 |
| 2013 | 7 | 34 |
| 2014 | 17 | 37 |
| 2015 | 21 | 36 |
| 2016 | 18 | 31 |
| 2017 | 35 | 47 |
| 2018 | 20 | 34 |
| 2019 | 27 | 32 |
| 2020 | 17 | 25 |
| 2021 | 13 | 33 |
| 2022 | 6 | 18 |
| 2023 | 13 | 26 |
| 2024 | 13 | 27 |
| 2025 | 13 | 25 |
| 2026 | 13 | 25 |
By publication year. Applications have been published since 2001. 2026 runs to 8 Oct.
Recent patents
- Methods of treating Prader Willi Syndrome and conditions associated with low basal metabolic rate or hyperphagia using a KATP channel opener29 Sep 2026US 12,746,244 B2Sedogen LLC
- Compositions for the treatment of hypertension7 Jul 2026US 12,673,047 B2The George Institute for Global Health
- Phosphodiesterase 3 (PDE3) inhibitors30 Jun 2026US 12,668,582 B2Zoetis Services LLC
- Compositions for the treatment of hypertension23 Jun 2026US 12,661,345 B2The George Institute for Global Health
- Antimicrobial fibres16 Jun 2026US 12,653,923 B2Advanced Medical Solutions Limited
- Concomitant use of diazoxide in treatment1 Oct 2026US 2026/0294926 A1Soleno Therapeutics, Inc.
- Compositions for the treatment of hypertension24 Sep 2026US 2026/0284022 A1The George Institute for Global Health
- Compositions for the treatment of hypertension3 Sep 2026US 2026/0256754 A1The George Institute for Global Health
- Induction of Proteasomal Activity in Mammalian Cells by Lifespan-extending tRNA Synthetase Inhibitors6 Aug 2026US 2026/0224523 A1UNM Rainforest Innovations
- Methods of treating prader willi syndrome and conditions associated with low basal metabolic rate or hyperphagia using a katp channel opener30 Jul 2026US 2026/0216203 A1Sedogen LLC
Most cited
By later US patents
- Quinoline derivatives as PI3 kinase inhibitors178US 8,138,347 B2GlaxoSmithKline LLC · 2012
- Local administration of phosphodiesterase inhibitors for the treatment of erectile dysfunction140US 6,037,346 AVivus, Inc. · 2000
- Methods for treatment of disorders of cardiac contractility108US 6,569,862 B1The Johns Hopkins University · 2003
- Methods for treatment of disorders of cardiac contractility106US 6,191,136 B1The Johns Hopkins University · 2001
- Maximizing effectiveness of substances used to improve health and well being104US 5,945,123 AK-V Pharmaceutical Company · 1999