A61K 31/4422
1,4-dihydropyridines
Official title: 1,4-Dihydropyridines, e.g. nifedipine, nicardipine
A61K31/4422 (1,4-dihydropyridines) appears on 453 US grants and 863 published applications in this corpus.
Search patents in A61K- Granted patents
- 453
- Published applications
- 863
- Assignees
- 446
- Inventors
- 1,523
- Latest grant
- 8 Sep 2026
Filings by year
| Year | Granted patents | Published applications |
|---|---|---|
| 1976 | 2 | 0 |
| 1977 | 0 | 0 |
| 1978 | 0 | 0 |
| 1979 | 0 | 0 |
| 1980 | 0 | 0 |
| 1981 | 0 | 0 |
| 1982 | 0 | 0 |
| 1983 | 0 | 0 |
| 1984 | 0 | 0 |
| 1985 | 0 | 0 |
| 1986 | 0 | 0 |
| 1987 | 0 | 0 |
| 1988 | 0 | 0 |
| 1989 | 0 | 0 |
| 1990 | 0 | 0 |
| 1991 | 0 | 0 |
| 1992 | 1 | 0 |
| 1993 | 2 | 0 |
| 1994 | 0 | 0 |
| 1995 | 0 | 0 |
| 1996 | 4 | 0 |
| 1997 | 6 | 0 |
| 1998 | 7 | 0 |
| 1999 | 15 | 0 |
| 2000 | 8 | 0 |
| 2001 | 12 | 2 |
| 2002 | 4 | 18 |
| 2003 | 10 | 24 |
| 2004 | 4 | 17 |
| 2005 | 8 | 22 |
| 2006 | 8 | 21 |
| 2007 | 1 | 13 |
| 2008 | 2 | 31 |
| 2009 | 3 | 28 |
| 2010 | 6 | 31 |
| 2011 | 5 | 27 |
| 2012 | 14 | 38 |
| 2013 | 10 | 25 |
| 2014 | 33 | 42 |
| 2015 | 21 | 45 |
| 2016 | 25 | 46 |
| 2017 | 20 | 34 |
| 2018 | 23 | 51 |
| 2019 | 32 | 50 |
| 2020 | 22 | 53 |
| 2021 | 34 | 41 |
| 2022 | 32 | 49 |
| 2023 | 21 | 44 |
| 2024 | 17 | 44 |
| 2025 | 26 | 33 |
| 2026 | 15 | 34 |
By publication year. Applications have been published since 2001. 2026 runs to 8 Oct.
Recent patents
- Liquisolid pharmaceutical formulation and process for manufacturing8 Sep 2026US 12,728,134 B2Rheinische Friedrich-Wilhelms-Universität Bonn
- Amlodipine formulations1 Sep 2026US 12,721,843 B2Azurity Pharmaceuticals, Inc.
- Compositions for the treatment of hypertension7 Jul 2026US 12,673,047 B2The George Institute for Global Health
- Safe and stable nimodipine formulation for injection and method for preparing same23 Jun 2026US 12,661,344 B2Baolong Pharmaceutical Co., Ltd.
- Compositions for the treatment of hypertension23 Jun 2026US 12,661,345 B2The George Institute for Global Health
- Amlodipine formulations8 Oct 2026US 2026/0306467 A1Azurity Pharmaceuticals, Inc.
- Compositions for the treatment of hypertension24 Sep 2026US 2026/0284022 A1The George Institute for Global Health
- Mek inhibitor for treatment of stroke24 Sep 2026US 2026/0284058 A1Edvince AB
- Compositions for sustained release of poorly soluble active ingredients10 Sep 2026US 2026/0263432 A1Prolevi Bio AB
- Compositions for the treatment of hypertension3 Sep 2026US 2026/0256754 A1The George Institute for Global Health
Most cited
By later US patents
- Methods and devices for providing prolonged drug therapy267US 6,919,373 B1Alza Corporation · 2005
- Methods for treating inflammatory conditions167US 6,190,691 B1Adolor Corporation · 2001
- Pharmaceutical composition containing acid addition salt of basic drug163US 6,255,502 B1Farmarc Nederland BV · 2001
- Method of producing multi-layer medicaments in solid form for oral or rectal administration124US 6,120,802 ABASF SE · 2000
- Methods and devices for providing prolonged drug therapy118US 6,930,129 B2Alza Corporation · 2005