A01K 67/0278
Knock-in vertebrates
Official title: Knock-in vertebrates, e.g. humanised vertebrates
A01K67/0278 (Knock-in vertebrates) appears on 1,125 US grants and 1,735 published applications in this corpus.
Search patents in A01K- Granted patents
- 1,125
- Published applications
- 1,735
- Assignees
- 607
- Inventors
- 2,347
- Latest grant
- 29 Sep 2026
Filings by year
| Year | Granted patents | Published applications |
|---|---|---|
| 1989 | 1 | 0 |
| 1990 | 0 | 0 |
| 1991 | 0 | 0 |
| 1992 | 1 | 0 |
| 1993 | 0 | 0 |
| 1994 | 3 | 0 |
| 1995 | 3 | 0 |
| 1996 | 10 | 0 |
| 1997 | 32 | 0 |
| 1998 | 41 | 0 |
| 1999 | 28 | 0 |
| 2000 | 30 | 0 |
| 2001 | 25 | 4 |
| 2002 | 22 | 47 |
| 2003 | 30 | 57 |
| 2004 | 14 | 51 |
| 2005 | 9 | 34 |
| 2006 | 26 | 48 |
| 2007 | 16 | 23 |
| 2008 | 21 | 28 |
| 2009 | 18 | 46 |
| 2010 | 20 | 33 |
| 2011 | 17 | 70 |
| 2012 | 25 | 44 |
| 2013 | 19 | 73 |
| 2014 | 41 | 86 |
| 2015 | 48 | 113 |
| 2016 | 50 | 100 |
| 2017 | 58 | 106 |
| 2018 | 66 | 89 |
| 2019 | 59 | 123 |
| 2020 | 64 | 102 |
| 2021 | 70 | 100 |
| 2022 | 61 | 76 |
| 2023 | 60 | 74 |
| 2024 | 54 | 82 |
| 2025 | 46 | 72 |
| 2026 | 37 | 54 |
By publication year. Applications have been published since 2001. 2026 runs to 8 Oct.
Recent patents
- Non-human animals having humanized Fc-gamma receptors29 Sep 2026US 12,745,761 B2Regeneron Pharmaceuticals, Inc.
- Genetically modified non-human animal with human or chimeric TFR122 Sep 2026US 12,740,550 B2Biocytogen Pharmaceuticals (Beijing) Co., Ltd.
- Rat models for CMT2A that develop a progressive neuropathy1 Sep 2026US 12,721,327 B2Charcot-Marie-Tooth Association
- Methods of treating mitochondrial disorders1 Sep 2026US 12,723,062 B2The Regents of the University of California
- Multi-transgenic pig for Xenotransplantation25 Aug 2026US 12,714,077 B2Revivicor, Inc.
- Transgenic model of human cardiomyopathy8 Oct 2026US 2026/0305586 A1Stichting Genetische Hartspierziekte PLN
- Humanized ace2-expressing transgenic mouse susceptible to sars-cov-2 virus infection and method for producing same8 Oct 2026US 2026/0305587 A1Seoul National University R&Db Foundation
- Genetically Modified Non-Human Animals and Methods of Use Thereof8 Oct 2026US 2026/0305588 A1Institute for Research in Biomedicine (IRB)
- Mouse model with humanized telomere1 Oct 2026US 2026/0293864 A1Washington State Univesity
- Single-sex chicken with toxin-antitoxin system1 Oct 2026US 2026/0293865 A1New York University
Most cited
By later US patents
- Transgenic non-human animals capable of producing heterologous antibodies of various isotypes1,748US 5,569,825 AGenPharm International, Inc. · 1996
- Transgenic non-human animals capable of producing heterologous antibodies1,680US 5,633,425 AGenPharm International, Inc. · 1997
- Transgenic non-human animals for producing heterologous antibodies1,604US 5,625,126 AGenPharm International, Inc. · 1997
- Production of antibodies from transgenic animals1,567US 5,545,807 AMedical Research Council · 1996
- Transgenic non-human animals capable of producing heterologous antibodies of various isotypes1,541US 5,661,016 AGenPharm International, Inc. · 1997