C12N 2840/445
For trans-splicing
Official title: for trans-splicing, e.g. polypyrimidine tract, branch point splicing
C12N2840/445 (For trans-splicing) appears on 44 US grants and 73 published applications in this corpus.
Search patents in C12N- Granted patents
- 44
- Published applications
- 73
- Assignees
- 56
- Inventors
- 135
- Latest grant
- 2 Jun 2026
Filings by year
| Year | Granted patents | Published applications |
|---|---|---|
| 1996 | 1 | 0 |
| 1997 | 1 | 0 |
| 1998 | 2 | 0 |
| 1999 | 3 | 0 |
| 2000 | 4 | 0 |
| 2001 | 2 | 0 |
| 2002 | 1 | 3 |
| 2003 | 2 | 6 |
| 2004 | 0 | 5 |
| 2005 | 1 | 4 |
| 2006 | 2 | 4 |
| 2007 | 0 | 0 |
| 2008 | 1 | 0 |
| 2009 | 2 | 3 |
| 2010 | 2 | 1 |
| 2011 | 0 | 2 |
| 2012 | 0 | 2 |
| 2013 | 0 | 4 |
| 2014 | 4 | 1 |
| 2015 | 0 | 3 |
| 2016 | 2 | 1 |
| 2017 | 0 | 1 |
| 2018 | 1 | 4 |
| 2019 | 2 | 2 |
| 2020 | 0 | 2 |
| 2021 | 1 | 2 |
| 2022 | 1 | 8 |
| 2023 | 2 | 2 |
| 2024 | 1 | 8 |
| 2025 | 5 | 3 |
| 2026 | 1 | 2 |
By publication year. Applications have been published since 2001. 2026 runs to 8 Oct.
Recent patents
- Systems and uses thereof for creating synthetic transcriptional logic ‘and’ gates based on pre-mRNA trans-splicing2 Jun 2026US 12,644,130 B2Migal Galilee Research Institute Ltd.
- Optimized acceptor splice site module for biological and biotechnological applications23 Dec 2025US 12,502,438 B2Vigeneron GmbH
- High-efficiency reconstitution of RNA molecules21 Oct 2025US 12,448,636 B2The Salk Institute for Biological Studies
- ABCA4 trans-splicing molecules9 Sep 2025US 12,410,440 B2Ascidian Therapeutics, Inc.
- Compositions and methods for expressing otoferlin15 Jul 2025US 12,359,221 B2The Regents of the University of California
- Abca4 trans-splicing molecules19 Feb 2026US 2026/0049332 A1Ascidian Therapeutics, Inc.
- High-efficiency reconstitution of rna molecules15 Jan 2026US 2026/0015642 A1The Salk Institute for Biological Studies
- Split prime editors11 Dec 2025US 2025/0376674 A1Prime Medicine, Inc.
- Compositions and methods for expressing otoferlin4 Dec 2025US 2025/0367325 A1The Regents of the University of California
- Intron fragments22 May 2025US 2025/0163455 A1Neuracle Genetics Inc.
Most cited
By later US patents
- Intron-mediated recombinant techniques and reagents151US 5,498,531 APresident and Fellows of Harvard College · 1996
- Methods and compositions for use in spliceosome mediated RNA trans-splicing71US 6,083,702 AIntronn Holdings LLC · 2000
- Chimeric RNA molecules generated by trans-splicing68US 6,013,487 A2000
- Intron-mediated recombinant techniques and reagents46US 5,780,272 APresident and Fellows of Harvard College · 1998
- Cell ablation using trans-splicing ribozymes41US 5,849,548 APresident and Fellows of Harvard College · 1998