C12N 2310/341
Gapmers, i.e. of the type ===---===
C12N2310/341 (Gapmers, i.e. of the type ===---===) appears on 1,060 US grants and 2,083 published applications in this corpus.
Search patents in C12N- Granted patents
- 1,060
- Published applications
- 2,083
- Assignees
- 371
- Inventors
- 1,783
- Latest grant
- 15 Sep 2026
Filings by year
| Year | Granted patents | Published applications |
|---|---|---|
| 1996 | 2 | 0 |
| 1997 | 5 | 0 |
| 1998 | 2 | 0 |
| 1999 | 39 | 0 |
| 2000 | 63 | 0 |
| 2001 | 50 | 5 |
| 2002 | 59 | 25 |
| 2003 | 25 | 183 |
| 2004 | 23 | 231 |
| 2005 | 15 | 85 |
| 2006 | 11 | 38 |
| 2007 | 16 | 49 |
| 2008 | 15 | 27 |
| 2009 | 20 | 46 |
| 2010 | 34 | 43 |
| 2011 | 25 | 47 |
| 2012 | 31 | 47 |
| 2013 | 30 | 39 |
| 2014 | 45 | 61 |
| 2015 | 37 | 71 |
| 2016 | 38 | 70 |
| 2017 | 49 | 69 |
| 2018 | 43 | 88 |
| 2019 | 51 | 81 |
| 2020 | 49 | 97 |
| 2021 | 57 | 114 |
| 2022 | 59 | 114 |
| 2023 | 45 | 112 |
| 2024 | 40 | 135 |
| 2025 | 50 | 122 |
| 2026 | 32 | 84 |
By publication year. Applications have been published since 2001. 2026 runs to 8 Oct.
Recent patents
- Compounds and methods for reducing FUS expression15 Sep 2026US 12,735,700 B2Ionis Pharmaceuticals, Inc.
- Antagonism as a therapy for TDP-43 proteinopathies25 Aug 2026US 12,716,065 B2University of Southern California
- Modulation of GYS1 expression25 Aug 2026US 12,716,067 B2Ionis Pharmaceuticals, Inc.
- Processes for the production of oligonucleotides9 Jun 2026US 12,649,939 B2GlaxoSmithKline Intellectual Property Development Limited
- Inhibition of lncExACT1 to treat heart disease26 May 2026US 12,637,674 B2The General Hospital Corporation
- Optimized gapmers antisense oligonucleotides for increasing foxg1 expression8 Oct 2026US 2026/0308582 A1EliGab Tx LLC
- Modulating apolipoprotein (a) expression8 Oct 2026US 2026/0308584 A1Ionis Pharmaceuticals, Inc.
- Methods of treatment of chronic kidney disease8 Oct 2026US 2026/0308590 A1AstraZeneca AB
- Oligonucleotide compositions and methods thereof1 Oct 2026US 2026/0297573 A1Wave Life Sciences Ltd.
- Oligonucleotides comprising segmented gap structures1 Oct 2026US 2026/0297584 A1Ausperbio Therapeutics Inc.
Most cited
By later US patents
- Oligoribonucleotides and ribonucleases for cleaving RNA486US 6,107,094 AIsis Pharmaceuticals, Inc. · 2000
- Hybrid oligonucleotide phosphorothioates427US 5,652,355 AWorcester Foundation for Experimental Biology · 1997
- Oligoribonucleotides for cleaving RNA385US 5,898,031 AIsis Pharmaceuticals, Inc. · 1999
- Lipid formulation340US 8,158,601 B2Alnylam Pharmaceuticals, Inc. · 2012
- Polycyclic sugar surrogate-containing oligomeric compounds and compositions for use in gene modulation323US 7,696,345 B2Isis Pharmaceuticals, Inc. · 2010