C12N 15/90
Stable introduction of foreign dna into chromosome
Official title: Stable introduction of foreign DNA into chromosome
C12N15/90 (Stable introduction of foreign dna into chromosome) appears on 2,885 US grants and 6,136 published applications in this corpus.
Search patents in C12N- Granted patents
- 2,885
- Published applications
- 6,136
- Assignees
- 1,690
- Inventors
- 9,252
- Latest grant
- 6 Oct 2026
Filings by year
| Year | Granted patents | Published applications |
|---|---|---|
| 1986 | 2 | 0 |
| 1987 | 3 | 0 |
| 1988 | 6 | 0 |
| 1989 | 11 | 0 |
| 1990 | 11 | 0 |
| 1991 | 7 | 0 |
| 1992 | 6 | 0 |
| 1993 | 12 | 0 |
| 1994 | 3 | 0 |
| 1995 | 9 | 0 |
| 1996 | 18 | 0 |
| 1997 | 22 | 0 |
| 1998 | 45 | 0 |
| 1999 | 42 | 0 |
| 2000 | 36 | 0 |
| 2001 | 39 | 5 |
| 2002 | 32 | 51 |
| 2003 | 44 | 72 |
| 2004 | 27 | 74 |
| 2005 | 20 | 63 |
| 2006 | 29 | 67 |
| 2007 | 28 | 34 |
| 2008 | 25 | 37 |
| 2009 | 15 | 49 |
| 2010 | 22 | 37 |
| 2011 | 27 | 69 |
| 2012 | 34 | 67 |
| 2013 | 39 | 60 |
| 2014 | 47 | 129 |
| 2015 | 42 | 140 |
| 2016 | 82 | 187 |
| 2017 | 83 | 208 |
| 2018 | 97 | 294 |
| 2019 | 146 | 408 |
| 2020 | 211 | 524 |
| 2021 | 205 | 533 |
| 2022 | 279 | 612 |
| 2023 | 267 | 642 |
| 2024 | 257 | 672 |
| 2025 | 343 | 620 |
| 2026 | 212 | 482 |
By publication year. Applications have been published since 2001. 2026 runs to 8 Oct.
Subgroups
Granted patents
Recent patents
- Composition for use in treating dystrophic epidermolysis bullosa6 Oct 2026US 12,751,974 B2Osaka University
- Engineered meganucleases having specificity for a recognition sequence in the hydroxyacid oxidase 1 gene6 Oct 2026US 12,752,019 B2Precision BioSciences, Inc.
- Mesothelin specific chimeric antigen receptors (CAR) for solid tumors cancer immunotherapy6 Oct 2026US 12,753,220 B2Cellectis
- Method for modulating RNA splicing by inducing base mutation at splice site or base substitution in polypyrimidine region6 Oct 2026US 12,753,420 B2Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences
- Engineered meganucleases having specificity for a recognition sequence in the transthyretin gene29 Sep 2026US 12,747,430 B2Precision BioSciences, Inc.
- Humanized ace2-expressing transgenic mouse susceptible to sars-cov-2 virus infection and method for producing same8 Oct 2026US 2026/0305587 A1Seoul National University R&Db Foundation
- Methods of preventing on-target genotoxicity induced by nucleases8 Oct 2026US 2026/0306552 A1Chu De Bordeaux
- Base editing approaches to treat abca4-associated stargardt disease8 Oct 2026US 2026/0306670 A1Massachusetts Eye and Ear Infirmary
- Genetically-modified t cells comprising a modified intron in the t cell receptor alpha gene8 Oct 2026US 2026/0308549 A1Precision BioSciences, Inc.
- Engineered compact crispr-cas12f system8 Oct 2026US 2026/0308554 A1
Most cited
By later US patents
- Ransgenic non-human animals for producing heterologous antibodies1,941US 5,545,806 AGenPharm International, Inc. · 1996
- Transgenic non-human animals capable of producing heterologous antibodies of various isotypes1,748US 5,569,825 AGenPharm International, Inc. · 1996
- Transgenic non-human animals capable of producing heterologous antibodies1,680US 5,633,425 AGenPharm International, Inc. · 1997
- Transgenic non-human animals for producing heterologous antibodies1,604US 5,625,126 AGenPharm International, Inc. · 1997
- Transgenic non-human animals capable of producing heterologous antibodies of various isotypes1,541US 5,661,016 AGenPharm International, Inc. · 1997