C07D 519/04
Dimeric indole alkaloids
Official title: Dimeric indole alkaloids, e.g. vincaleucoblastine
C07D519/04 (Dimeric indole alkaloids) appears on 138 US grants and 63 published applications in this corpus.
Search patents in C07D- Granted patents
- 138
- Published applications
- 63
- Assignees
- 64
- Inventors
- 288
- Latest grant
- 28 Apr 2026
Filings by year
| Year | Granted patents | Published applications |
|---|---|---|
| 1976 | 5 | 0 |
| 1977 | 3 | 0 |
| 1978 | 9 | 0 |
| 1979 | 7 | 0 |
| 1980 | 8 | 0 |
| 1981 | 9 | 0 |
| 1982 | 8 | 0 |
| 1983 | 3 | 0 |
| 1984 | 3 | 0 |
| 1985 | 2 | 0 |
| 1986 | 1 | 0 |
| 1987 | 5 | 0 |
| 1988 | 9 | 0 |
| 1989 | 6 | 0 |
| 1990 | 4 | 0 |
| 1991 | 5 | 0 |
| 1992 | 1 | 0 |
| 1993 | 1 | 0 |
| 1994 | 1 | 0 |
| 1995 | 1 | 0 |
| 1996 | 0 | 0 |
| 1997 | 1 | 0 |
| 1998 | 0 | 0 |
| 1999 | 0 | 0 |
| 2000 | 2 | 0 |
| 2001 | 0 | 0 |
| 2002 | 1 | 1 |
| 2003 | 0 | 2 |
| 2004 | 1 | 2 |
| 2005 | 0 | 4 |
| 2006 | 1 | 2 |
| 2007 | 4 | 3 |
| 2008 | 1 | 5 |
| 2009 | 1 | 2 |
| 2010 | 3 | 5 |
| 2011 | 3 | 0 |
| 2012 | 2 | 5 |
| 2013 | 3 | 0 |
| 2014 | 2 | 1 |
| 2015 | 2 | 3 |
| 2016 | 1 | 4 |
| 2017 | 3 | 1 |
| 2018 | 0 | 3 |
| 2019 | 3 | 4 |
| 2020 | 2 | 3 |
| 2021 | 5 | 3 |
| 2022 | 2 | 2 |
| 2023 | 0 | 2 |
| 2024 | 2 | 2 |
| 2025 | 1 | 3 |
| 2026 | 1 | 1 |
By publication year. Applications have been published since 2001. 2026 runs to 8 Oct.
Recent patents
- Multi-cyclic IRAK and FLT3 inhibiting compounds and uses thereof28 Apr 2026US 12,612,410 B2Children's Hospital Medical Center
- Polypeptides antagonizing Wnt signaling in tumor cells29 Apr 2025US 12,285,493 B2Ablynx N. V.
- Dosage form of vinca alkaloid drug31 Dec 2024US 12,178,812 B2Sun Pharmaceutical Industries Limited
- Methods of preparing cytotoxic benzodiazepine derivatives14 May 2024US 11,981,687 B2ImmunoGen, Inc.
- Method and means for manufacturing terpene indole alkaloids30 Aug 2022US 11,427,842 B2John Innes Centre
- Process for the fluorination and/or cyclization of an amino alkene or alkyne in a continuous stream and facility for performing the process7 May 2026US 2026/0125349 A1Centre National De La Recherche Scientifique
- Prodrug kit for multi-pronged chemotherapy18 Dec 2025US 2025/0381202 A1
- Polypeptides antagonizing wnt signaling in tumor cells13 Nov 2025US 2025/0345448 A1Ablynx N. V.
- Heterocyclic glp-1 agonists3 Apr 2025US 2025/0109148 A1Gasherbrum Bio, Inc.
- Multi-cyclic irak and flt3 inhibiting compounds and uses thereof5 Sep 2024US 2024/0294530 A1Kurome Therapeutics, Inc.
Most cited
By later US patents
- Conjugates of a vinca derivative carrying a detergent chain in the C-3 position68US 5,024,835 AIre-Celltarg S.A. · 1991
- Amide derivatives of VLB, leurosidine, leurocristine and related dimeric alkaloids57US 4,203,898 AEli Lilly and Company · 1980
- Vinblastin-23-oyl amino acid derivatives43US 4,639,456 AOmnichem · 1987
- Conjugates of vinblastine, a process for their preparation and their use in therapy39US 4,870,162 AOmnichem · 1989
- Vinblastin-23-oyl amino acid derivatives for use as antitumor agents38US 4,388,305 AOmnichem · 1983