C07D 498/18
Bridged systems
C07D498/18 (Bridged systems) appears on 801 US grants and 864 published applications in this corpus.
Search patents in C07D- Granted patents
- 801
- Published applications
- 864
- Assignees
- 389
- Inventors
- 2,467
- Latest grant
- 6 Oct 2026
Filings by year
| Year | Granted patents | Published applications |
|---|---|---|
| 1976 | 1 | 0 |
| 1977 | 1 | 0 |
| 1978 | 5 | 0 |
| 1979 | 7 | 0 |
| 1980 | 5 | 0 |
| 1981 | 11 | 0 |
| 1982 | 11 | 0 |
| 1983 | 4 | 0 |
| 1984 | 2 | 0 |
| 1985 | 0 | 0 |
| 1986 | 0 | 0 |
| 1987 | 4 | 0 |
| 1988 | 2 | 0 |
| 1989 | 3 | 0 |
| 1990 | 7 | 0 |
| 1991 | 10 | 0 |
| 1992 | 24 | 0 |
| 1993 | 23 | 0 |
| 1994 | 18 | 0 |
| 1995 | 17 | 0 |
| 1996 | 36 | 0 |
| 1997 | 16 | 0 |
| 1998 | 10 | 0 |
| 1999 | 13 | 0 |
| 2000 | 10 | 0 |
| 2001 | 10 | 1 |
| 2002 | 14 | 18 |
| 2003 | 13 | 21 |
| 2004 | 5 | 16 |
| 2005 | 10 | 30 |
| 2006 | 8 | 28 |
| 2007 | 22 | 28 |
| 2008 | 18 | 34 |
| 2009 | 19 | 30 |
| 2010 | 19 | 22 |
| 2011 | 12 | 19 |
| 2012 | 20 | 30 |
| 2013 | 19 | 31 |
| 2014 | 20 | 28 |
| 2015 | 34 | 31 |
| 2016 | 20 | 44 |
| 2017 | 34 | 37 |
| 2018 | 25 | 25 |
| 2019 | 29 | 34 |
| 2020 | 27 | 44 |
| 2021 | 22 | 52 |
| 2022 | 31 | 52 |
| 2023 | 34 | 60 |
| 2024 | 35 | 61 |
| 2025 | 32 | 53 |
| 2026 | 29 | 35 |
By publication year. Applications have been published since 2001. 2026 runs to 8 Oct.
Recent patents
- P38alpha mitogen-activated protein kinase inhibitors6 Oct 2026US 12,753,184 B2Gen1E Lifesciences Inc.
- Macrocyclic glucagon-like peptide 1 receptor agonists15 Sep 2026US 12,735,433 B2Eli Lilly and Company
- Fused tetracyclic quinazoline derivatives as inhibitors of ERBB215 Sep 2026US 12,735,434 B2Enliven, Inc.
- Rifamycin analogs and antibody-drug conjugates thereof25 Aug 2026US 12,715,881 B2Regeneron Pharmaceuticals, Inc.
- Maytansinoid derivatives, conjugates thereof, and methods of use28 Jul 2026US 12,691,182 B2Regeneron Pharmaceuticals, Inc.
- Ras inhibitors1 Oct 2026US 2026/0297112 A1Revolution Medicines, Inc.
- Sik2 modulators and uses thereof17 Sep 2026US 2026/0274820 A1Nimbus Salacia, Inc.
- Kif modulator compounds and methods of use10 Sep 2026US 2026/0265254 A1Iambic Therapeutics, Inc.
- Mtorc modulators and uses thereof10 Sep 2026US 2026/0265272 A1Aeovian Pharmaceuticals, Inc.
- Targeted theranostic agents for imaging and treating cancer20 Aug 2026US 2026/0242354 A1Board of Regents, The University of Texas System
Most cited
By later US patents
- Dechloromaytansinoids, their pharmaceutical compositions and method of use302US 4,256,746 ATakeda Chemical Industries, Ltd. · 1981
- Maytansinoids302US 4,322,348 ATakeda Chemical Industries, Ltd. · 1982
- Maytansinoids302US 4,331,598 ATakeda Chemical Industries, Ltd. · 1982
- Chemotherapeutically active maytansinoids from Trewia nudiflora301US 4,313,946 AThe United States of America as represented by the Secretary of Agriculture · 1982
- Maytansinoids300US 4,364,866 ATakeda Chemical Industries, Ltd. · 1982