C07D 243/14
1,4-benzodiazepines
Official title: 1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
C07D243/14 (1,4-benzodiazepines) appears on 596 US grants and 401 published applications in this corpus.
Search patents in C07D- Granted patents
- 596
- Published applications
- 401
- Assignees
- 236
- Inventors
- 1,345
- Latest grant
- 26 May 2026
Filings by year
| Year | Granted patents | Published applications |
|---|---|---|
| 1976 | 17 | 0 |
| 1977 | 37 | 0 |
| 1978 | 22 | 0 |
| 1979 | 11 | 0 |
| 1980 | 12 | 0 |
| 1981 | 16 | 0 |
| 1982 | 25 | 0 |
| 1983 | 19 | 0 |
| 1984 | 4 | 0 |
| 1985 | 3 | 0 |
| 1986 | 2 | 0 |
| 1987 | 1 | 0 |
| 1988 | 5 | 0 |
| 1989 | 4 | 0 |
| 1990 | 1 | 0 |
| 1991 | 5 | 0 |
| 1992 | 1 | 0 |
| 1993 | 10 | 0 |
| 1994 | 9 | 0 |
| 1995 | 9 | 0 |
| 1996 | 10 | 0 |
| 1997 | 22 | 0 |
| 1998 | 17 | 0 |
| 1999 | 14 | 0 |
| 2000 | 10 | 0 |
| 2001 | 8 | 6 |
| 2002 | 14 | 18 |
| 2003 | 15 | 17 |
| 2004 | 12 | 22 |
| 2005 | 9 | 16 |
| 2006 | 20 | 23 |
| 2007 | 20 | 25 |
| 2008 | 14 | 23 |
| 2009 | 16 | 16 |
| 2010 | 7 | 22 |
| 2011 | 5 | 10 |
| 2012 | 13 | 19 |
| 2013 | 8 | 10 |
| 2014 | 16 | 13 |
| 2015 | 17 | 14 |
| 2016 | 7 | 15 |
| 2017 | 3 | 8 |
| 2018 | 6 | 4 |
| 2019 | 32 | 30 |
| 2020 | 14 | 21 |
| 2021 | 10 | 13 |
| 2022 | 12 | 12 |
| 2023 | 4 | 9 |
| 2024 | 10 | 14 |
| 2025 | 11 | 11 |
| 2026 | 7 | 10 |
By publication year. Applications have been published since 2001. 2026 runs to 8 Oct.
Subgroups
Granted patents
Recent patents
- Histone deacetylase inhibitors26 May 2026US 12,637,433 B2The University of Queensland
- Metabotropic glutamate receptor negative allosteric modulators (NAMs) and uses thereof26 May 2026US 12,637,436 B2Sanford Burnham Prebys Medical Discovery Institute
- Specification of functional cranial placode derivatives from human pluripotent stem cells5 May 2026US 12,618,044 B2Memorial Sloan Kettering Cancer Center
- 3-phenylpropylamine derivative21 Apr 2026US 12,606,533 B2Daiichi Sankyo Company, Limited
- Deuterated 1,4-benzodiazepine-2,5-dione compound and use thereof17 Mar 2026US 12,577,213 B2Ningbo Combireg Pharmaceutical Technology Co., Ltd.
- Compositions comprising 2,2,4-trimethyl-n-phenyl-1,2- dihydroquinolin-6-amine17 Sep 2026US 2026/0274805 A1Flexsys IP Holdings, LLC
- Polymorphs of bis(fluoroalkyl)-1,4-benzodiazepinone compounds and uses thereof10 Sep 2026US 2026/0265206 A1Bristol-Myers Squibb Company
- Compositions comprising bisfluoroalkyl-1,4-benzodiazepinone compounds for treating adenoid cystic carcinoma11 Jun 2026US 2026/0158041 A1Immunome, Inc.
- Polymorphs of bis(fluoroalkyl)-1,4-benzodiazepinone compounds and uses thereof4 Jun 2026US 2026/0152473 A1Bristol-Myers Squibb Company
- Synthesis of trans-8-chloro-5-methyl-1-[4-(pyridin-2-yloxy)-cyclohexyl]-5,6-dihydro-4h-2,3,5,10b-tetraaza-benzo[e]azulene and crystalline forms thereof14 May 2026US 2026/0132137 A1Hoffmann-La Roche Inc.
Most cited
By later US patents
- Solid phase and combinatorial synthesis of benzodiazepine compounds on a solid support822US 5,288,514 AThe Regents of the University of California · 1994
- Complex combinatorial chemical libraries encoded with tags344US 5,565,324 ACold Spring Harbor Laboratory · 1996
- Complex combinatorial chemical libraries encoded with tags118US 5,721,099 ACold Spring Harbor Laboratory · 1998
- Benzodiazepine analogs114US 4,820,834 AMerck & Co., Inc. · 1989
- Solid phase and combinatorial synthesis of compounds on a solid support105US 5,545,568 AThe Regents of the University of California · 1996