C07D 239/78
With hetero atoms directly attached in position 2
Official title: with hetero atoms directly attached in position 2
C07D239/78 (With hetero atoms directly attached in position 2) appears on 444 US grants and 473 published applications in this corpus.
Search patents in C07D- Granted patents
- 444
- Published applications
- 473
- Assignees
- 250
- Inventors
- 1,787
- Latest grant
- 22 Sep 2026
Filings by year
| Year | Granted patents | Published applications |
|---|---|---|
| 1976 | 6 | 0 |
| 1977 | 3 | 0 |
| 1978 | 5 | 0 |
| 1979 | 6 | 0 |
| 1980 | 4 | 0 |
| 1981 | 2 | 0 |
| 1982 | 6 | 0 |
| 1983 | 3 | 0 |
| 1984 | 4 | 0 |
| 1985 | 7 | 0 |
| 1986 | 5 | 0 |
| 1987 | 4 | 0 |
| 1988 | 8 | 0 |
| 1989 | 1 | 0 |
| 1990 | 5 | 0 |
| 1991 | 1 | 0 |
| 1992 | 2 | 0 |
| 1993 | 3 | 0 |
| 1994 | 2 | 0 |
| 1995 | 4 | 0 |
| 1996 | 4 | 0 |
| 1997 | 4 | 0 |
| 1998 | 4 | 0 |
| 1999 | 2 | 0 |
| 2000 | 4 | 0 |
| 2001 | 7 | 3 |
| 2002 | 9 | 8 |
| 2003 | 3 | 20 |
| 2004 | 10 | 12 |
| 2005 | 7 | 25 |
| 2006 | 11 | 23 |
| 2007 | 9 | 18 |
| 2008 | 8 | 11 |
| 2009 | 6 | 17 |
| 2010 | 17 | 22 |
| 2011 | 17 | 21 |
| 2012 | 14 | 17 |
| 2013 | 24 | 12 |
| 2014 | 16 | 20 |
| 2015 | 20 | 24 |
| 2016 | 13 | 18 |
| 2017 | 21 | 20 |
| 2018 | 13 | 25 |
| 2019 | 24 | 18 |
| 2020 | 19 | 24 |
| 2021 | 16 | 19 |
| 2022 | 14 | 25 |
| 2023 | 11 | 27 |
| 2024 | 13 | 22 |
| 2025 | 17 | 14 |
| 2026 | 6 | 8 |
By publication year. Applications have been published since 2001. 2026 runs to 8 Oct.
Subgroups
Granted patents
Recent patents
- Sodium 2-[(4S)-8-fluoro-2-[4-(3-methoxyphenyl)piperazin-1-y1]-3-[2-methoxy-5-(trifluoromethyl)phenyl]-4H-quinazolin-4-yl]acetate monohydrate, its preparation and use22 Sep 2026US 12,741,943 B2AIC246 AG & Co. KG
- Potassium salt of 2-[(4S)-8-fluoro-2-[4-(3-methoxyphenyl)piperazin-1-yl]-3-[2-methoxy-5-(trifluoromethyl)phenyl]-4H-quinazolin-4-yl]acetic acid4 Aug 2026US 12,698,262 B2AIC246 AG & Co. KG
- Method of producing a crystalline form of sodium 2-[(4S)-8-fluoro-2-[4-(3- methoxyphenyl)piperazin-1-yl]-3-[2-methoxy-5-(trifluoromethyl)phenyl]-4H-quinazoline-4-yl]acetate trihydrate16 Jun 2026US 12,655,110 B2AIC246 AG & Co. KG
- Substituted pyrrolo[3,4-b]pyridines as PI3K-α inhibitors17 Mar 2026US 12,581,252 B2D. E. Shaw Research, LLC
- PCSK9 inhibitors and methods of use thereof17 Feb 2026US 12,552,807 B2AstraZeneca AB
- Protein kinase inhibitors and uses thereof1 Oct 2026US 2026/0297035 A1DELiver Therapeutics, Inc.
- Precipitation process for amorphous letermovir1 Oct 2026US 2026/0297036 A1Lupin Limited
- 2-oxoquinazoline derivatives as methionine adenosyltransferase 2a inhibitors30 Jul 2026US 2026/0217709 A1Ideaya Biosciences, Inc.
- Pi3k-alpha inhibitors and methods of use thereof16 Jul 2026US 2026/0205746 A1D. E. Shaw Research, LLC
- Compounds and methods for treating cancer18 Jun 2026US 2026/0166051 A1The Regents of the University of California
Most cited
By later US patents
- Benzimidazoles for ischemic heart conditions96US 5,693,652 AEisai Co., Ltd. · 1997
- Inhibitors of the fibroblast growth factor receptor89US 8,802,697 B2Blueprint Medicines Corporation · 2014
- Fused heterocyclic compounds87US 7,615,552 B2Synta Pharmaceuticals Corp. · 2009
- Piperidinylalkyl quinazoline compounds, composition and method of use85US 4,335,127 AJanssen Pharmaceutica NV · 1982
- Substituted quinazolines as inhibitors of KRAS G12C80US 9,840,516 B2Araxes Pharma LLC · 2017