PCSK9 inhibitors and methods of use thereof

A compound of Formula (I)

• or pharmaceutically acceptable salt thereof, wherein:
• A is selected from H, halo, hydroxy, unsubstituted alkyl, thioalkyl, alkenyl, alkoxy, acyloxy, cyano, cycloalkyl, —C(O)OR6, and —C(O)NR6R7;
• B is selected from H, alkyl, and halo;
• X is NR5;
• n is 0, and R1 and R1′, together with the atoms to which they are attached, form a cyclopentyl ring which is unsubstituted or substituted with one or more hydroxy;
• R2 is selected from H, halo, alkyl, alkoxy, amidoalkyl, aminoalkyl, hydroxyalkyl, alkylamino, cyano, and hydroxy;
• R2′ is selected from H, halo, alkyl, alkoxy, amidoalkyl, aminoalkyl, and cyano;
• R5 is H or alkyl;
• each R6 and R7 is independently H or alkyl;
• and
• Y is selected from substituted aryl, substituted heteroaryl, unsubstituted, and substituted heterocyclyl.