A61K 38/2242
Atrial natriuretic factor complex: atriopeptins, atrial natriuretic protein [anp]
Official title: {Atrial natriuretic factor complex: Atriopeptins, atrial natriuretic protein [ANP]; Cardionatrin, Cardiodilatin}
A61K38/2242 (Atrial natriuretic factor complex: atriopeptins, atrial natriuretic protein [anp]) appears on 156 US grants and 285 published applications in this corpus.
Search patents in A61K- Granted patents
- 156
- Published applications
- 285
- Assignees
- 119
- Inventors
- 397
- Latest grant
- 30 Jun 2026
Filings by year
| Year | Granted patents | Published applications |
|---|---|---|
| 1988 | 3 | 0 |
| 1989 | 0 | 0 |
| 1990 | 0 | 0 |
| 1991 | 3 | 0 |
| 1992 | 0 | 0 |
| 1993 | 1 | 0 |
| 1994 | 0 | 0 |
| 1995 | 4 | 0 |
| 1996 | 2 | 0 |
| 1997 | 2 | 0 |
| 1998 | 0 | 0 |
| 1999 | 2 | 0 |
| 2000 | 0 | 0 |
| 2001 | 0 | 2 |
| 2002 | 1 | 2 |
| 2003 | 0 | 1 |
| 2004 | 4 | 7 |
| 2005 | 1 | 9 |
| 2006 | 2 | 14 |
| 2007 | 1 | 8 |
| 2008 | 1 | 9 |
| 2009 | 5 | 11 |
| 2010 | 5 | 16 |
| 2011 | 2 | 11 |
| 2012 | 7 | 12 |
| 2013 | 10 | 22 |
| 2014 | 14 | 20 |
| 2015 | 11 | 19 |
| 2016 | 12 | 21 |
| 2017 | 14 | 12 |
| 2018 | 12 | 15 |
| 2019 | 3 | 5 |
| 2020 | 5 | 10 |
| 2021 | 7 | 9 |
| 2022 | 3 | 12 |
| 2023 | 7 | 14 |
| 2024 | 3 | 8 |
| 2025 | 5 | 9 |
| 2026 | 4 | 7 |
By publication year. Applications have been published since 2001. 2026 runs to 8 Oct.
Recent patents
- Combination therapy with controlled-release CNP agonists30 Jun 2026US 12,667,604 B2Ascendis Pharma Growth Disorders A/S
- Assessing and treating acute decompensated heart failure23 Jun 2026US 12,661,388 B2Mayo Foundation for Medical Education and Research
- Preventing cytokine release syndrome3 Mar 2026US 12,564,622 B2The Johns Hopkins University
- Use of C-type natriuretic peptide variants to treat skeletal dysplasia6 Jan 2026US 12,514,906 B2Biomarin Pharmaceutical Inc.
- Formulations of MANP and uses thereof30 Sep 2025US 12,427,185 B2E-Star Biotech, LLC
- Methods of Lowering Blood Pressure Using Fixed Doses of MANP1 Oct 2026US 2026/0295012 A1E-Star Biotech, LLC
- Assessing and treating acute decompensated heart failure17 Sep 2026US 2026/0273021 A1Mayo Foundation for Medical Education and Research
- Method of Treatment of a Thoracolumbar Deformity in a Human Subject with Achondroplasia10 Sep 2026US 2026/0263563 A1
- Preventing cytokine release syndrome13 Aug 2026US 2026/0232770 A1The Johns Hopkins University
- Use of analog of c-type natriuretic peptide for the treatment of fgfr-related bone repair and bone formation impairment18 Jun 2026US 2026/0166127 A1Assistance Publique-HôPitaux De Paris (Aphp)
Most cited
By later US patents
- Orally administerable ANF123US 4,983,402 AClinical Technologies Associates, Inc. · 1991
- Reversible pegylated drugs106US 7,585,837 B2Yeda Research and Development Co. Ltd. · 2009
- Process for the preparation of microspheres made of a biodegradable polymeric material93US 5,445,832 ADebio Recherche Pharmaceutique S. A. · 1995
- Method and composition for treatment of skeletal dysplasias74US 7,276,481 B2ProChon Biotech Ltd. · 2007
- Pharmaceutical composition for the treatment of acute disorders48US 6,761,910 B1Diabact AB · 2004