A61K 31/499
Spiro-condensed pyrazines or piperazines
A61K31/499 (Spiro-condensed pyrazines or piperazines) appears on 89 US grants and 184 published applications in this corpus.
Search patents in A61K- Granted patents
- 89
- Published applications
- 184
- Assignees
- 105
- Inventors
- 598
- Latest grant
- 12 May 2026
Filings by year
| Year | Granted patents | Published applications |
|---|---|---|
| 2001 | 1 | 0 |
| 2002 | 0 | 1 |
| 2003 | 0 | 1 |
| 2004 | 0 | 1 |
| 2005 | 0 | 1 |
| 2006 | 1 | 4 |
| 2007 | 1 | 3 |
| 2008 | 0 | 0 |
| 2009 | 1 | 0 |
| 2010 | 0 | 3 |
| 2011 | 0 | 5 |
| 2012 | 1 | 1 |
| 2013 | 3 | 9 |
| 2014 | 6 | 10 |
| 2015 | 8 | 6 |
| 2016 | 4 | 5 |
| 2017 | 4 | 16 |
| 2018 | 12 | 14 |
| 2019 | 9 | 12 |
| 2020 | 9 | 9 |
| 2021 | 10 | 14 |
| 2022 | 7 | 10 |
| 2023 | 5 | 10 |
| 2024 | 2 | 15 |
| 2025 | 3 | 14 |
| 2026 | 2 | 20 |
By publication year. 2026 runs to 8 Oct.
Recent patents
- Compounds for targeted protein degradation12 May 2026US 12,624,035 B2Amphista Therapeutics Limited
- Therapeutic approach to lung disease13 Jan 2026US 12,521,389 B2The Children’s Hospital of Philadelphia
- Pyrazole MAGL inhibitors25 Mar 2025US 12,258,340 B2H. Lundbeck A.S.
- Compositions and methods for treating neurological disorders4 Mar 2025US 12,239,637 B2Rush University Medical Center
- RET inhibitors, pharmaceutical compositions and uses thereof28 Jan 2025US 12,209,085 B2Sunshine Lake Pharma Co., Ltd.
- Inhibitors of spinster homolog 2 (spns2) for use in therapy1 Oct 2026US 2026/0297044 A1University of Virginia Patent Foundation
- Inhibitors of cyclin-dependent kinase (cdk) 12 and/or cdk13 and uses thereof1 Oct 2026US 2026/0297091 A1Insilico Medicine IP Limited
- Parg inhibitory compounds24 Sep 2026US 2026/0284069 A1Forx Therapeutics AG
- Pyrazole-fused compounds as vrk1 inhibitors17 Sep 2026US 2026/0272918 A1
- Rifabutin analogs for the treatment of bacterial diseases13 Aug 2026US 2026/0234161 A1Bioversys AG
Most cited
By later US patents