A61K 31/485
Morphinan derivatives
Official title: Morphinan derivatives, e.g. morphine, codeine
A61K31/485 (Morphinan derivatives) appears on 3,016 US grants and 5,145 published applications in this corpus.
Search patents in A61K- Granted patents
- 3,016
- Published applications
- 5,145
- Assignees
- 1,350
- Inventors
- 4,884
- Latest grant
- 29 Sep 2026
Filings by year
| Year | Granted patents | Published applications |
|---|---|---|
| 1976 | 6 | 0 |
| 1977 | 4 | 0 |
| 1978 | 3 | 0 |
| 1979 | 0 | 0 |
| 1980 | 6 | 0 |
| 1981 | 5 | 0 |
| 1982 | 7 | 0 |
| 1983 | 18 | 0 |
| 1984 | 16 | 0 |
| 1985 | 10 | 0 |
| 1986 | 16 | 0 |
| 1987 | 13 | 0 |
| 1988 | 19 | 0 |
| 1989 | 22 | 0 |
| 1990 | 12 | 0 |
| 1991 | 17 | 0 |
| 1992 | 11 | 0 |
| 1993 | 17 | 0 |
| 1994 | 14 | 0 |
| 1995 | 16 | 0 |
| 1996 | 21 | 0 |
| 1997 | 21 | 0 |
| 1998 | 32 | 0 |
| 1999 | 56 | 0 |
| 2000 | 37 | 0 |
| 2001 | 45 | 24 |
| 2002 | 38 | 70 |
| 2003 | 31 | 163 |
| 2004 | 50 | 145 |
| 2005 | 23 | 121 |
| 2006 | 60 | 118 |
| 2007 | 32 | 139 |
| 2008 | 33 | 126 |
| 2009 | 21 | 130 |
| 2010 | 55 | 172 |
| 2011 | 53 | 178 |
| 2012 | 82 | 161 |
| 2013 | 123 | 225 |
| 2014 | 161 | 305 |
| 2015 | 170 | 357 |
| 2016 | 212 | 393 |
| 2017 | 218 | 349 |
| 2018 | 178 | 284 |
| 2019 | 168 | 263 |
| 2020 | 161 | 276 |
| 2021 | 169 | 267 |
| 2022 | 136 | 212 |
| 2023 | 108 | 184 |
| 2024 | 103 | 187 |
| 2025 | 119 | 162 |
| 2026 | 68 | 134 |
By publication year. Applications have been published since 2001. 2026 runs to 8 Oct.
Recent patents
- API stability in softgels29 Sep 2026US 12,746,206 B2R.P. Scherer Technologies, LLC
- Use of dextromethorphan in combination with CYP2D6 and CYP3A4 enzyme inhibitors for the treatment of pain29 Sep 2026US 12,746,235 B2Biobina LLC
- Treatment of inflammatory diseases of the central nervous system29 Sep 2026US 12,746,245 B2Palmaya Pty Ltd
- Treatment of agitation associated with Alzheimer's disease with a combination of bupropion and dextromethorphan22 Sep 2026US 12,740,949 B2Antecip Bioventures II LLC
- Naltrexone formulation15 Sep 2026US 12,734,167 B2Intas Pharmaceuticals Ltd.
- Compounds and combinations thereof for treating neurological and psychiatric conditions8 Oct 2026US 2026/0306426 A1Antecip Bioventures II LLC
- Rapid induction with monthly injectable buprenorphine extended-release8 Oct 2026US 2026/0306480 A1Indivior UK Limited
- Rapid induction with monthly injectable buprenorphine extended-release8 Oct 2026US 2026/0306481 A1Indivior UK Limited
- Composition, methods and uses8 Oct 2026US 2026/0306509 A14E Therapeutics, Inc.
- Pharmaceutical compositions comprising bupropion and cysteine8 Oct 2026US 2026/0306637 A1Antecip Bioventures II LLC
Most cited
By later US patents
- Wound dressing with conformable elastomeric wound contact layer1,263US 5,445,604 ASmith and Nephew Associated Companies Limited · 1995
- Controlled release oxycodone compositions466US 5,508,042 AEuro-Celtigue, S.A. · 1996
- Orally administrable opioid formulations having extended duration of effect437US 5,968,551 APurdue Pharma L. P. · 1999
- Controlled release oxycodone compositions436US 5,266,331 AEuroceltique, S.A. · 1993
- Opioid overdose monitoring412US 10,932,729 B2Masimo Corporation · 2021