A61K 31/4168
Having a nitrogen attached in position 2
Official title: having a nitrogen attached in position 2, e.g. clonidine
A61K31/4168 (Having a nitrogen attached in position 2) appears on 399 US grants and 701 published applications in this corpus.
Search patents in A61K- Granted patents
- 399
- Published applications
- 701
- Assignees
- 302
- Inventors
- 1,072
- Latest grant
- 1 Sep 2026
Filings by year
| Year | Granted patents | Published applications |
|---|---|---|
| 1990 | 1 | 0 |
| 1991 | 0 | 0 |
| 1992 | 0 | 0 |
| 1993 | 0 | 0 |
| 1994 | 0 | 0 |
| 1995 | 0 | 0 |
| 1996 | 3 | 0 |
| 1997 | 1 | 0 |
| 1998 | 6 | 0 |
| 1999 | 7 | 0 |
| 2000 | 6 | 0 |
| 2001 | 8 | 1 |
| 2002 | 5 | 13 |
| 2003 | 6 | 22 |
| 2004 | 1 | 14 |
| 2005 | 2 | 13 |
| 2006 | 7 | 15 |
| 2007 | 2 | 9 |
| 2008 | 3 | 20 |
| 2009 | 3 | 29 |
| 2010 | 9 | 20 |
| 2011 | 7 | 34 |
| 2012 | 16 | 33 |
| 2013 | 16 | 41 |
| 2014 | 30 | 53 |
| 2015 | 29 | 37 |
| 2016 | 30 | 50 |
| 2017 | 30 | 43 |
| 2018 | 32 | 31 |
| 2019 | 24 | 40 |
| 2020 | 24 | 35 |
| 2021 | 26 | 37 |
| 2022 | 16 | 30 |
| 2023 | 16 | 31 |
| 2024 | 15 | 18 |
| 2025 | 9 | 21 |
| 2026 | 9 | 11 |
By publication year. Applications have been published since 2001. 2026 runs to 8 Oct.
Recent patents
- Stable pharmaceutical compositions of clonidine1 Sep 2026US 12,721,837 B2Azurity Pharmaceuticals, Inc.
- Creatine and/or creatinine compositions and related methods23 Jun 2026US 12,661,316 B2ThermoLife International, LLC
- Methods of treatment and/or prevention of disorders and symptoms related to BKCa and/or SK channelophathies21 Apr 2026US 12,605,367 B2
- Liposomal sustained-release compositions containing a therapeutic drug and use thereof14 Apr 2026US 12,599,557 B2Taiwan Liposome Co., Ltd.
- Prevention of accumulated tolerance to stimulant medication for the treatment of ADHD7 Apr 2026US 12,594,250 B2
- Stable pharmaceutical compositions of clonidine8 Oct 2026US 2026/0306456 A1Azurity Pharmaceuticals, Inc.
- Multilamellar Vesicle Drug Formulation3 Sep 2026US 2026/0256694 A1
- Antibacterial and synergistic active compound and use thereof27 Aug 2026US 2026/0250257 A1East China University of Science and Technology
- Usp2 inhibitors and methods of using the same for the treatment of diseases20 Aug 2026US 2026/0242394 A1Beth Israel Deaconess Medical Center, Inc.
- Antifungal compositions and methods of use thereof6 Aug 2026US 2026/0224574 A1Arizona Board of Regents on Behalf of the University of Arizona
Most cited
By later US patents
- Sustained release, comfort formulation for glaucoma therapy329US 4,911,920 AAlcon Laboratories, Inc. · 1990
- Urologic irrigation solution and method for inhibition of pain, inflammation and spasm152US 5,858,017 AOmeros Medical Systems, Inc. · 1999
- Arthroscopic irrigation solution and method for inhibition of pain and inflammation140US 5,860,950 AOmeros Medical Systems, Inc. · 1999
- Vascular irrigation solution and method for inhibition of pain, inflammation, spasm and restenosis118US 5,800,385 AOmeros Medical Systems, Inc. · 1998
- Drug depots having different release profiles for reducing, preventing or treating pain and inflammation102US 8,470,360 B2Warsaw Orthopedic, Inc. · 2013