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US RE39,847 E1Granted
Method of treating a systemic disease
AssigneeKos Life Sciences, Inc.
InventorsAkwete L. Adjei, Anthony J. Cutie
Life of this patent
Estimating the term…
Abstract
A method of treating a systemic disease in a patient in need of such treatment is disclosed. The method comprising maintaining the inspiratory flow rate and volume of the patient to a certain value and then administering a medicament aerosol formulation to such patient.
Claims8
A method of treating a systemic disease in a patient in need thereof, which consists essentially of:
- (a) maintaining the inspiratory flow rate in the patient in a range of about 0.05 to about 2 liters per second and the inspiratory volume of the patient in the range of about 0.1 to about 5 liters;
- and
- (b) administering to the patient a medicinal aerosol formulation comprising
- (a′) a medicament present in an effective amount;
- and ,
- (b′) a fluid propellant carrier for carrying said transporting said medicament to the patient at a suitable dosing time of about 200 to about 2000 milliseconds for a suitable dosing period and
- (c′) a stabilizer selected from the group consisting of an amino acid, a derivative thereof, a water addition stabilizer and a mixture of any of the foregoing.
4 more elements
A method of treating a systemic disease in a patient in need thereof which comprises:
- (a) administering to the patient a medicinal aerosol formulation comprising (a′) a medicament present in an effective amount;
- (b′) a fluid propellent carrier for carrying and transporting said medicament at a suitable dosing time for a suitable dosing period;
- and (c′) a stabilizer selected from the group consisting of (1) an amino acid (2) a derivative thereof;
- (3) a water addition stabilizer and (4) a mixture of any of the foregoing stabilizers;
- and
- (b) maintaining the inspiratory flow rate in the patient in a range of about 0.05 to about 2 liters per second and the inspiratory volume of the patient in the range of about 0.1 to about 5 liters.
3 more elements
Dependencies are inferred from the claim text.