Method of evaluating a procedure for determining the aggregate dose received in the course of a radiotherapy treatment

A non-transitory computer-readable medium comprising a computer program product stored thereon, which is comprises program code instructions to execute a method when the instructions are executed on a computer, wherein the method comprises:

• evaluating a procedure for determining an aggregate dose received during a radiotherapy treatment, called a procedure to be evaluated, wherein the evaluating comprises:
• generating a 3D digital deformable model corresponding to an anatomical region
• by defining the 3D digital deformable model for at least one organ to be treated and at least one neighboring organ, and
• by using said model, generating a series of simulated images interpretable by the procedure to be evaluated;
• obtaining a reference aggregate dose for said at least one organ to be treated and at least one neighboring organ;
• the procedure to be evaluated delivering, on the basis of at least one image of the series of simulated images, an aggregate dose;
• delivering at least one piece of information representing quality of said procedure to be evaluated by comparing the reference aggregate dose with the aggregate dose delivered by said procedure to be evaluated,
• said reference aggregate dose being obtained in taking account of anatomical deformations applied to said organs so as to determine a reference dose effectively received by said organs at each treatment session as a function of at least one of their shape or their real position during this session;
• and
• improving said procedure for determining the aggregate dose as a function of the comparison of the reference aggregate dose with the aggregate dose delivered by said procedure.

A method, implemented by a computing device, for evaluating a procedure for determining an aggregate dose received during a radiotherapy treatment, called a procedure to be evaluated, said procedure to be evaluated being implemented by a treatment device, said method comprising:

• evaluating the procedure for determining an aggregate dose received during a radiotherapy treatment, wherein the evaluating comprises:
• the computing device generating a 3D digital deformable model corresponding to an anatomical region
• by defining the 3D digital deformable model for at least one organ to be treated and at least one neighboring organ, and
• by using said model, generating a series of simulated images interpretable by the procedure to be evaluated;
• the computing device obtaining a reference aggregate dose for said at least one organ to be treated and at least one neighboring organ;
• the procedure to be evaluated delivering, on the basis of at least one image of the series of simulated images, an aggregate dose;
• the computing device delivering at least one piece of information representing quality of said procedure to be evaluated by comparing the reference aggregate dose with the aggregate dose delivered by said procedure to be evaluated;
• the computing device obtaining said reference aggregate dose by taking account of anatomical deformations applied to said organs so as to determine a reference dose effectively received by said organs at each treatment session as a function of at least one of their shape or their real position during this session,
• wherein obtaining said reference aggregate dose includes the following acts:
• generating a model comprising said at least one organ to be treated and said at least one neighboring organ;
• determining a field of deformation of said organs from at least one rule of deformation and/or progress of said organ;
• obtaining a series of images of said model at different instants, called simulated images, comprising at least one image representing a planning scanner and a series of tracking images each corresponding to a session of treatment;
• planning a treatment on the basis of at least one of said simulated images by using a treatment planning system implementing said procedure for determining radiotherapy doses so as to obtain a planned dose and parameters of a set of radiation ballistics;
• determining one set of doses per fraction, each corresponding to one of said sessions;
• and
• determining said reference aggregate dose in applying said deformation field to each tracking image so as to determine said effectively received reference dose;
• and
• the computing device improving said procedure for determining the aggregate dose as a function of the comparison of the reference aggregate dose with the aggregate dose delivered by said procedure.