Antimicrobial compositions and methods for locking catheters
AssigneeBecton, Dickinson and Company
InventorMinh Quang Hoang
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Abstract
Antimicrobial compositions for use in locking catheters and other devices are provided. In some embodiments, the composition includes at least one alcohol, at least one biocidal agent which is not an alcohol, and one or more poloxamers; in other embodiments, the composition comprises at least one poloxamer and at least one alcohol. The composition can provide long-lasting antimicrobial activity. Methods of using the composition are also provided.
Claims23
A catheter containing a locking solution comprising an antimicrobial composition, the antimicrobial composition comprising:
- at least one poloxamer;
- at least 10 weight percent of at least one alcohol on a basis of total weight of the antimicrobial composition;
- and
- about 0.01 wt. % to about 10 wt. % on the basis of total weight of the antimicrobial composition of at least one biocidal agent that is not an alcohol.
A catheter comprising a coating comprising an antimicrobial composition, the antimicrobial composition comprising:
- 0.1 weight percent on a basis of total weight of the antimicrobial composition to 2 weight percent of at least one poloxamer;
- at least 10 weight percent of at least one C1-C6 lower alcohol on a basis of total weight of the antimicrobial composition;
- about 0.01 wt. % to about 10 wt. % on the basis of total weight of the antimicrobial composition of at least one biocidal agent that is not an alcohol;
- and
- an anticoagulant.
A method for providing disinfection of an implanted catheter comprising a lumen and a wall, the method comprising:
- introducing a locking solution comprising an antimicrobial composition into the lumen of the catheter, the antimicrobial composition comprising:
- at least one poloxamer;
- at least 10 weight percent of at least one alcohol on a basis of total weight of the antimicrobial composition;
- and
- about 0.01 wt. % to about 10 wt. % on the basis of total weight of the antimicrobial composition of at least one biocidal agent that is not an alcohol.
Dependencies are inferred from the claim text.