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US 9,872,908 B2Granted
Oral composition for delivery of drugs and other substances
AssigneeAvanti Polar Lipids, Inc.
InventorsWalter A Shaw, Stephen W Burgess, Shengrong Li
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Abstract
The present disclosure provides for a composition which may be used for the solublization of an agent or the oral administration of an agent, the composition comprising, a lyosphosphatidyl compound and at least one of a monoglyceride and a free fatty acid. In certain embodiments, the composition comprises a lyosphosphatidyl compound, a monoglyceride and a free fatty acid. In certain embodiments, the composition comprises an agent, a lyosphosphatidyl compound, a monoglyceride and a free fatty acid.
Claims15
A composition for solubilizing an agent, the composition comprising:
- a lysophosphatidyl compound of the general formula IC, a monoglyceride of the general formula IV and a free fatty acid of the general formula V:
- wherein,
- R1 is a saturated or unsaturated carbon chain;
- Linker is a linking portion;
- one of R4, R5 and R6 is —C(O)—R7 and the remaining of R4, R5 and R6 are each independently selected from H or R8;
- R7 and R9 are each independently a saturated or unsaturated carbon chain from 1 to 21 carbons in length;
- and
- R8 is saturated or unsaturated carbon chain from 1 to 10 carbons in length.
5 more elements
Dependencies are inferred from the claim text.