Back to results
US 9,872,849 B2Granted
Diterpenoid membranolide compounds having anti-leishmania activity and uses thereof
AssigneeUniversity of South Florida
InventorsBill J. Baker, Christopher G. Witowski, John Alan Maschek, Brian Vesely, Dennis E. Kyle
Life of this patent
Estimating the term…
Abstract
In a screening program, the Antarctic sponge Dendrilla membranosa was found to produce diterpenoid secondary metabolites with activity against the leishmaniasis-causing parasite Leishmania donovani. The present invention concerns compositions useful for control of Leishmania spp. parasites in vitro and in vivo and treatment of leishmaniasis; methods for treatment of leishmaniasis; and methods for controlling Leishmania spp. parasites in vitro and in vivo.
Claims8
A composition comprising at least one anti-Leishmania agent;
- and at least one other compound having the following chemical structure:
- or a pharmaceutically acceptable salt thereof;
- or,
- or a pharmaceutically acceptable salt thereof.
1 more element
Dependencies are inferred from the claim text.