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US 9,872,840 B2Granted
Effect of garcinol in delaying the progression of diabetic nephropathy
AssigneeDelhi Institute of Pharmaceutical Sciences and Research
InventorsSonia Gandhi, B. P. Srinivasan
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Abstract
The present invention relates to the use of garcinol as a nephroprotective agent. The present invention also relates to the use of garcinol as a therapeutic agent in renal disorders, in particular diabetic nephropathy, and to medicinal preparations containing garcinol. Further disclosed herein are method of treatment of renal disorders, in particular diabetic nephropathy by administration of garcinol.
Claims12
A method of providing Garcinol to a subject that has diabetic nephropathy comprising:
- selecting a subject that has diabetic nephropathy;
- and
- providing said subject an amount of Garcinol in the range of 100 mg/kg to 1000 mg/kg bodyweight of said subject, thereby inhibiting progression of diabetic nephropathy in the subject.
The method as claimed in 1, wherein the amount of nitric oxide is reduced in said subject.
Dependencies are inferred from the claim text.