Compositions and methods for diagnosing or treating neutrophil-mediated inflammatory disease
AssigneeThe Board of Trustees of the University of Illinois
InventorsZhenjia Wang, Jaehyung Cho, Asrar Malik
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Abstract
Disclosed are nanoparticle compositions comprising nanoparticles prepared from denatured, cross-linked albumin and a therapeutic agent for treating a neutrophil-mediated inflammation, and methods of treating neutrophil-mediated inflammation using the compositions.
Claims13
A method of treating a neutrophil-mediated inflammatory disease in a subject in need of treatment comprising:
- administering to the subject a therapeutically effective amount of a composition comprising nanoparticles, each nanoparticle consisting of denatured, cross-linked albumin and a therapeutic agent, the nanoparticles selectively binding to and internalized by activated neutrophils.
A composition comprising nanoparticles, each nanoparticle consisting of denatured, cross-linked albumin and a therapeutic agent, the nanoparticles selectively binding to and internalized by activated neutrophils.
Dependencies are inferred from the claim text.