Eosinophil peroxidase compositions and methods of their use
AssigneeExOxEmis, Inc.
InventorsJackson T. Stephens, Jr., Matthew J. Pete
Life of this patent
Estimating the term…
Abstract
Eosinophil peroxidase compositions and methods of their use for killing and/or inhibiting the growth of susceptible microorganisms are provided. The compositions include an eosinophil peroxidase, a peroxide or peroxide source, and amino acids glycine, L-alanine, and L-proline.
Claims17
A composition for killing or inhibiting the growth of non-sporular bacteria, comprising:
- (a) an eosinophil peroxidase;
- (b) glucose oxidase;
- and
- (c) amino acids glycine, L-alanine, and L-proline, wherein the amino acids enhance the antibacterial activity of the eosinophil peroxidase.
A binary combination for killing or inhibiting the growth of non-sporular bacteria, comprising:
- (a) a first composition comprising an eosinophil peroxidase;
- glucose oxidase;
- and amino acids glycine, L-alanine, and L-proline, wherein the amino acids enhance the antibacterial activity of the eosinophil peroxidase;
- and
- (b) a second composition comprising glucose,
- wherein the binary combination is effective for killing or inhibiting the growth of non-sporular bacteria when the first composition and the second composition are combined in a single solution and come in contact with the non-sporular bacteria.
A binary combination for killing or inhibiting the growth of non-sporular bacteria, comprising:
- (a) a first composition comprising an eosinophil peroxidase;
- glucose oxidase;
- and amino acids glycine, L-alanine, and L-proline, wherein the amino acids enhance the antibacterial activity of the eosinophil peroxidase;
- and
- (b) a second composition comprising glucose,
- wherein the binary combination is effective for killing or inhibiting the growth of non-sporular bacteria when the first composition and the second composition are each in solution form and are applied concurrently to the non-sporular bacteria.
A binary combination for killing or inhibiting the growth of non-sporular bacteria, comprising:
- (a) a first composition comprising an eosinophil peroxidase;
- glucose oxidase;
- and amino acids glycine, L-alanine, and L-proline, wherein the amino acids enhance the antibacterial activity of the eosinophil peroxidase;
- and
- (b) a second composition comprising glucose,
- wherein the binary combination is effective for killing or inhibiting the growth of non-sporular bacteria when the first composition and the second composition are each in solution form and are applied sequentially to the non-sporular bacteria.
Dependencies are inferred from the claim text.