Back to results
US 9,775,348 B2Granted
Composition comprising a sesterterpene and use thereof as antibiotic and antifungal adjuvant
AssigneeRode Pharma S.R.L.
InventorsLuigi Amelotti, Lorenzo Secondini
Life of this patent
Estimating the term…
Abstract
The present invention relates to a composition comprising at least a sesterterpene for use as medicament like antibiotic or antifungal. Furthermore, the present invention relates to the use of at least a sesterterpene for increasing, assisting and/or enhancing the bacteriostatic and/or bactericidal activity of an antibiotic or the fungicidal activity of an antifungal compound.
Claims15
A method for treating a subject, the method comprising:
- administering to the subject a terpene selected from the group consisting of gascardic acid and a salt thereof, geranyl pyrophosphate and geranylfarnesol pyrophosphate in an effective amount to treat bacteria, fungi or infections caused therefrom in the subject, wherein the bacteria are selected from the group consisting of Staphylococcus aureus, Staphylococcus aureus subsp rosen and Staphylococcus epidermidis, Pseudomonas, Escherichia coli, Bacillus, Proteus vulgaris, Legionella, Salmonella, Listeria monocytogenes, Clostridium difficile, Streptococcus pyogenes, Enterococcus fecaiis, Enterococcus hirae, and Kiebsielia pneumoniae;
- and the fungi are selected from the group consisting of Aspergillus niger, Aspergillus versicolor and Aspergillus clavatus, Candida albicans, Trichoderma, Peniciiiiurn funirolosum, Chaetoimium giobosum, Fusarium rubrum, Fusarium oxysoorum, Fusarium solani, Puliularia fermantans and Rhizoous spp.
Dependencies are inferred from the claim text.