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US 9,751,915 B2Granted
Mutant pores
AssigneeOxford Nanopore Technologies PLC
InventorsJames Clarke, Andrew John Heron, Lakmal Jayasinghe, Elizabeth Jayne Wallace, James White
Life of this patent
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Abstract
The invention relates to mutant forms of Msp. The invention also relates to nucleic acid characterization using Msp.
Claims26
A mutant Msp monomer comprising a variant of the sequence shown in SEQ ID NO:
- 2, wherein the variant comprises a mutation at least one of the following positions of SEQ ID NO:
- 2:
- position 75, position 77, position 88 and position 126.
A construct comprising two or more covalently attached Msp monomers.
Dependencies are inferred from the claim text.