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US 9,751,903 B2Granted
Pharmaceutical compounds for use in the therapy of clostridium difficile infection
AssigneeETH Zurich
InventorsBastien Castagner, Jean-Christophe Leroux, Mattias Ivarsson, Gisbert Schneider, Anna Pratsinis
Life of this patent
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Abstract
The invention relates to a compound described by a general formula (1), wherein each X independently from other X can be OPO32−, OPSO22− or OSO3−; R1 is a solubility function such as a polyethylene glycol moiety. The invention further relates to the use of the compounds according to the invention in the therapy of infection by Clostridium difficile.
Claims19
A compound described by a general formula (1)
- wherein R1 is a solubility function R2 selected from the group consisting of
- a polyethylene glycol and
- a polyglycerol,
- and each X independently of any other X is selected from OPO32−, OPSO22−,or OSO3−.
1 more element
A compound described by a general formula (1)
- wherein R1 is a polyethylene glycol, each X independently of any other X is selected from OPO32−, OPSO22−, or OSO3−, and wherein said polyethylene glycol is described by a formula (R3—(O—CH2—CH2)2—) with R3 being hydrogen, methyl or ethyl.
Dependencies are inferred from the claim text.