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US 9,751,853 B2Granted
Solid forms of 3-(5-amino-2-methyl-4-oxo-4H-quinazolin-3-yl)-piperidine-2,6-dione, and their pharmaceutical compositions and uses
AssigneeCelgene Corporation
InventorsGeorge W. Muller, Hon-Wah Man, Benjamin M. Cohen, Ying Li, Jean Xu, William W. Leong
Life of this patent
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Abstract
Solid forms comprising 3-(5-amino-2-methyl-4-oxo-4H-quinazolin-3-yl)-piperidine-2,6-dione, compositions comprising the solid forms, methods of making the solid forms and methods of their uses are disclosed.
Claims10
A method of treating or managing a disease or disorder comprising administering to a patient having the disease or disorder a solid form comprising a hydrochloride salt of 3-(5-amino-2-methyl-4-oxo-4H-quinazolin-3-yl)-piperidine-2,6-dione:
- having an X-ray powder diffraction pattern comprising peaks at approximately 8.6° 2θ, 13.1° 2θ, 20.5° 2θ and 26.3° 2θ, wherein the disease or disorder is leukemia, lymphoma, myeloma, myelodysplastic syndrome, or myeloproliferative disease.
Dependencies are inferred from the claim text.