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AssigneeThomas Swan & Co. Ltd.
InventorsDavid Dunn, Howard Winston Tyrrell Sutton, John Ing Chuan Daly, Simon Jonathon Grant, Lian Hutchings, Patrice Georges Antonin Ribiere, Matthew Richard Gibbings, Sergio Aaron Gamboa Martinez, Craig Anderson, Yulia Rogan
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A catalyst, method of using, and use of a hydrogenation catalyst, preferably palladium on a support, preferably alumina or activated charcoal support. This in the presence of lithium salts, with salts such as the borates being preferred. This provides hydrogenation of precursors to give rise to a stereoselective, such as diastereoselective bias in the product of alkene hydrogenation using the catalyst. This equation, using the preferred substrate, best illustrates the invention:
A method of stereoselective hydrogenation, the method comprising providing a substrate of formula:
Dependencies are inferred from the claim text.