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US 9,751,826 B2Granted
4-vinyl-2-cyclopenten-1-one derivatives, the production thereof, and the use of same as an antibiotic agent
AssigneeCentre National de la Recherche Scientifique (CNRS)
InventorsJamal Ouazzani, Emilie Adelin, Geraldine Le Goff
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Abstract
The invention relates to a compound of general formula (I) wherein: R1 is a hydrogen atom or a C1 to C4 alkyl radical; R2 is a C1 to C4 hydroxyl or alkoxyl radical; and R3 and R4 are independently a hydrogen atom or a C1 à C4 alkyl radical; and the enantiomers and mixtures of enantiomers thereof, especially in a racemic form.
Claims7
A method of treating a bacterial infection in a subject comprising administering to a subject in need thereof, an effective amount of a compound of the following general formula (I):
- wherein:
- R1 is a hydrogen atom or a C1 to C4 alkyl radical;
- R2 is a C1 to C4 hydroxyl or alkoxyl radical, and
- R3 and R4 are independently a hydrogen atom or a C1 to C4 alkyl radical;
- the enantiomers and mixtures of enantiomers thereof;
- and wherein the infection is a bacterial infection selected from among the group consisting of an Escherichia, Klebsiella, Enterobacter, Micrococcus, Bacillus, Streptococcus, Acinetobacter, and Stapylococcus infection.
3 more elements
Dependencies are inferred from the claim text.